Dihydromyricetin
- CAS No.
- 27200-12-0
- Chemical Name:
- Dihydromyricetin
- Synonyms
- ampeloptin;AMPELOPSIN;Two hydrogenMyricetin;vine tea extract dihydromyricetin;3,3’,4’,5,5’,7-hexahydroxy-flavanon;DihydroMyricetin, froM Myrica rubra;3,3’,4’,5,5’,7-hexahydroxy-2,3-dihydroflavanonol;2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on;3,3',4',5,5;,(2r-trans)-
- CBNumber:
- CB1670507
- Molecular Formula:
- C15H12O8
- Molecular Weight:
- 320.25
- MOL File:
- 27200-12-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
| storage temp. | -20°C |
|---|---|
| solubility | DMSO: ≥5mg/mL (warmed) |
| form | powder |
| Boiling point | 780.7±60.0 °C(Predicted) |
| Density | 1.808±0.06 g/cm3(Predicted) |
| Melting point | 239-241 °C |
| pka | 7.38±0.60(Predicted) |
| color | white to beige |
| Stability | Hygroscopic |
| InChI | InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1 |
| InChIKey | KJXSIXMJHKAJOD-LSDHHAIUSA-N |
| SMILES | [C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O |
| LogP | 1.230 (est) |
| CAS DataBase Reference | 27200-12-0 |
Dihydromyricetin price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 42866 | Dihydromyricetin analytical standard | 27200-12-0 | 10MG | ₹16042.65 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D5464 | Dihydromyricetin | 27200-12-0 | 200MG | ₹5700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5464 | Dihydromyricetin | 27200-12-0 | 1G | ₹8800 | 2022-05-26 | Buy |
Dihydromyricetin Chemical Properties,Uses,Production
Description
Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities，and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).
Uses
Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.
Definition
ChEBI: (+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin.
Dihydromyricetin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +86-18374838656 | China | 1025 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | China | 2605 | 58 | Inquiry |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
| Changyi Longchang Bio-Chemical Co., LTD | +86-13256193735; +8613256193735 | China | 964 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | China | 5867 | 58 | Inquiry |
| Bonerge(Hunan) Lifescience Co., Ltd. | +86-731-82791134 +86-18801900056 | China | 30 | 58 | Inquiry |
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