Myricetin
- CAS No.
- 529-44-2
- Chemical Name:
- Myricetin
- Synonyms
- MYRICETOL;bayberry bark extract;MYRICETIN 95%;CANNABISCETIN;3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one;MYRISETIN;MYRICETIN;NSC 407290;LDN 0014058;Myricetin>
- CBNumber:
- CB5142262
- Molecular Formula:
- C15H10O8
- Molecular Weight:
- 318.24
- MOL File:
- 529-44-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | >300 °C(lit.) |
|---|---|
| Boiling point | 377.41°C (rough estimate) |
| Density | 1.4222 (rough estimate) |
| refractive index | 1.4395 (estimate) |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble10mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow |
| pka | 6.30±0.40(Predicted) |
| form | crystalline |
| color | Yellowish Brown |
| Water Solubility | Soluble in dimethyl sulfoxide,dimethyl formamide and ethanol. Insoluble in water. |
| Merck | 14,6332 |
| BRN | 332331 |
| Stability | Hygroscopic |
| InChIKey | IKMDFBPHZNJCSN-UHFFFAOYSA-N |
| LogP | 1.206 (est) |
| CAS DataBase Reference | 529-44-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | LK8646000 |
| F | 10 |
| HS Code | 29329990 |
Myricetin price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M6760 | Myricetin ≥96.0%, crystalline | 529-44-2 | 10MG | ₹7122.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M6760 | Myricetin ≥96.0%, crystalline | 529-44-2 | 25MG | ₹14104.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 70050 | Myricetin ≥96.0% (HPLC) | 529-44-2 | 25MG | ₹14353.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 72576 | Myricetin analytical standard | 529-44-2 | 10MG | ₹14635.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 70050 | Myricetin ≥96.0% (HPLC) | 529-44-2 | 100MG | ₹45573.25 | 2022-06-14 | Buy |
Myricetin Chemical Properties,Uses,Production
Description
Myricetin[529-44-2] is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant. Myricetin inhibits TBARS formation with an IC50 value of 6.34 and at 20 μM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression. Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.
Chemical Properties
The substance is a brown-yellow to brown-green crystalline powder. It can dissolve in methanol, ethanol, acetone, and ethyl acetate, and has a low solubility in water. It is not soluble in chloroform and petroleum ether. This compound is derived from the fruit of Myrica rubra (Lour.) Sieb. et Zucc. and belongs to the Populus family.
Uses
Myricetin is used as an antioxidant. It is a cell-permeable flavonoid used in inflammatory, diabetes, and cancer studies. It is effective in protecting neurons against oxidative stresses. Further, it inhibits yeast alfa-glucosidase,1 glyoxalase I in vitro and bovine milk xanthine oxidase.
Definition
ChEBI: Myricetin is a hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants. It has a role as a cyclooxygenase 1 inhibitor, an antineoplastic agent, an antioxidant, a plant metabolite, a food component, a hypoglycemic agent and a geroprotector. It is a hexahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a myricetin(1-).
General Description
Myricetin is a novel flavanoid compound useful as chemotherapeutic, chemopreventive, and antiangiogenic agent. It also acts as an antioxidant, anti-inflammatory, and anti-cancer agent, and can inhibit the activity of reverse transcriptase.
Purification Methods
Myricetin (Cannabiscetin, 3,3',4',5,5',7-hexahydroxyflavone) [529-44-2] M 318.2, m > 3 0 0o, 357o(dec) (polyphenolic pKEst~8-11). Recrystallise myricetin from aqueous EtOH (m 357o dec, as monohydrate) or Me2CO (m 350o dec, with one mol of Me2CO) as yellow crystals. It is almost insoluble in CHCl3 and AcOH. The hexaacetate has m 213o. [Hergert J Org Chem 21 534 1956, Spada & Cameroni Gazzetta 86 965, 975 1956, Kalff & Robinson J Chem Soc 127 181 1925, Beilstein 18/5 V 670.]
Myricetin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +8618374838656 | China | 1025 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12458 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5989 | 58 | Inquiry |
Related articles
- Preparation of Myricetin
- Myricetin(MYR) belongs to flavonoids, mainly exists in the stems and leaves of vine tea or the bark and leaves of bayberry.
- Sep 15，2022
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