Ethyl 3-methyl-3-phenylglycidate
- CAS No.
- 77-83-8
- Chemical Name:
- Ethyl 3-methyl-3-phenylglycidate
- Synonyms
- ALDEHYDE C-16;Strawberry;ETHYL METHYL PHENYL GLYCIDATE;FEMA 2444;ETHYL 2,3-EPOXY-3-PHENYLBUTYRATE;Fraeseol;c-16aldehyde;bayberry aldehyde;STRAWBERRY ALDEHYDE;2,3-epoxy-3-phenyl-butanoicaciethylester
- CBNumber:
- CB9126747
- Molecular Formula:
- C12H14O3
- Molecular Weight:
- 206.24
- MOL File:
- 77-83-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/27 13:40:29
| Boiling point | 272-275 °C(lit.) |
|---|---|
| Density | 1.087 g/mL at 25 °C(lit.) |
| FEMA | 2444 | ETHYL METHYLPHENYLGLYCIDATE |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| form | clear liquid |
| color | Colorless to Light orange to Yellow |
| Odor | at 100.00 %. sweet fruity strawberry floral honey fatty |
| Odor Type | fruity |
| JECFA Number | 1577 |
| BRN | 12299 |
| LogP | 2.43 |
| CAS DataBase Reference | 77-83-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Glycidic acid, 3-methyl-3-phenyl, ethyl ester(77-83-8) |
| EPA Substance Registry System | Ethyl methylphenylglycidate (77-83-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H411 | |||||||||
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 10-36/37/38 | |||||||||
| Safety Statements | 16-26-36/37/39 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | MW5250000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29189090 | |||||||||
| Toxicity | LD50 orally in Rabbit: 5470 mg/kg | |||||||||
| NFPA 704 |
|
Ethyl 3-methyl-3-phenylglycidate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W244406 | Ethyl 3-methyl-3-phenylglycidate ≥98%, FCC, FG | 77-83-8 | 1SAMPLE-K | ₹5141.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W244406 | Ethyl 3-methyl-3-phenylglycidate ≥98%, FCC, FG | 77-83-8 | 1KG | ₹6971.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W244406 | Ethyl 3-methyl-3-phenylglycidate ≥98%, FCC, FG | 77-83-8 | 5KG | ₹19420.05 | 2022-06-14 | Buy |
| TCI Chemicals (India) | E0873 | Ethyl 3-Methyl-3-phenylglycidate (mixture of isomers) min. 95.0 %(total of isomer) | 77-83-8 | 25G | ₹1500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | E0873 | Ethyl 3-Methyl-3-phenylglycidate (mixture of isomers) min. 95.0 %(total of isomer) | 77-83-8 | 250G | ₹2800 | 2022-05-26 | Buy |
Ethyl 3-methyl-3-phenylglycidate Chemical Properties,Uses,Production
Chemical Properties
Ethyl 3-Methyl-3-phenylglycidate exists as two optically active pairs of cis- and trans-isomers; each isomer has a characteristic odor . The commercial product is a racemic mixture of all four isomers and has a strong, sweetish, strawberry odor. The cis/trans ratio obtained in the Darzens condensation of acetophenone (R==CH3) and ethyl chloroacetate depends on the base used in the reaction.
Occurrence
Has apparently not been reported to occur in nature.
Uses
Ethyl 3-methyl-3-phenylglycidate is a synthetic flavoring agent that is a glycidic acid ester. It is a colorless to pale yellow liquid with a strong fruit odor suggestive of strawberries. It is unstable to alkali and moderately stable to weak organic acids. It should be stored in glass, tin, or aluminum containers. It is soluble in fixed oils and in propylene glycol. It is used in flavors for strawberry note and has application in candy, beverages, and ice cream at 6–20 ppm. It is also termed aldehyde c-16.
Preparation
By reaction of acetophenone and the ethyl ester of monochloroacetic acid in the presence of an alkaline condensing agent.
General Description
Clear, colorless to yellowish liquid with a strawberry-like odor.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Esters, such as Ethyl 3-methyl-3-phenylglycidate, react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Fire Hazard
Ethyl 3-methyl-3-phenylglycidate is probably combustible.
Trade name
Strawberry pure (Givaudan)
Safety Profile
Mddly toxic by ingestion. Mutation data reported. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.
Synthesis
Ethyl 3-methyl-3-phenylglycidate is synthesized by Acetophenone by condensation with Ethyl monochloroacetate in an alkaline solution, using sodium as a condensing agent.
Solubility in organics
Poorly soluble in Propylene glycol, Glycerin and mineral oil, soluble in alcohol, miscible with most perfume and flavor oils.
Ethyl 3-methyl-3-phenylglycidate Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| HJ AROCHEM | +91-8690768060 +91-9724420086 | Ahmedabad, India | 171 | 58 | Inquiry |
| Garuda Chemicals | +91-8097853976 +91-8097853975 | Maharashtra, India | 58 | 58 | Inquiry |
| Desicca Chemicals | +91-7777090620 +91-9821128366 | Maharashtra, India | 20 | 58 | Inquiry |
| Mruchem | +91-8087147166 +91-8087147166 | Gujarat, India | 52 | 58 | Inquiry |
| Shraddha Organics | -9427214514 | Gujarat, India | 14 | 58 | Inquiry |
| Santo Righello Pvt. Ltd | 91-9885571757 | Hyderabad, India | 919 | 58 | Inquiry |
| Acorn Chemicals Pvt. Ltd. | 91-22-22818122 | Maharashtra, India | 22 | 58 | Inquiry |
| Prasad Organics (P) Ltd. | 91-44-24503549 | Tamil Nadu, India | 9 | 58 | Inquiry |
| Akshaya Laboratories Pvt. Ltd | -64642624 | Hyderabad, India | 125 | 58 | Inquiry |
| Nagar Haveli Perfumes & Aromatics | +91 9867078149 | Mumbai, India | 149 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| HJ AROCHEM | 58 |
| Garuda Chemicals | 58 |
| Desicca Chemicals | 58 |
| Mruchem | 58 |
| Shraddha Organics | 58 |
| Santo Righello Pvt. Ltd | 58 |
| Acorn Chemicals Pvt. Ltd. | 58 |
| Prasad Organics (P) Ltd. | 58 |
| Akshaya Laboratories Pvt. Ltd | 58 |
| Nagar Haveli Perfumes & Aromatics | 58 |