Glycidyl phenyl ether
- CAS No.
- 122-60-1
- Chemical Name:
- Glycidyl phenyl ether
- Synonyms
- PGE;2-(PHENOXYMETHYL)OXIRANE;PHENYL GLYCIDYL ETHER;1,2-EPOXY-3-PHENOXYPROPANE;ageflexpge;heloxywc-63;Ageflex pge;PHENYLGYCIDYLETHER;PHENYLGLYCIDOLETHER;PHENYL GLYCID ETHER
- CBNumber:
- CB2429443
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.17
- MOL File:
- 122-60-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/7 14:06:06
| Melting point | 3.5 °C(lit.) |
|---|---|
| Boiling point | 245-247 °C(lit.) |
| Density | 1.109 g/mL at 25 °C(lit.) |
| vapor density | 5.2 (vs air) |
| vapor pressure | 0.03 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | 2.4g/l |
| form | Liquid |
| color | Clear colorless to yellow |
| Water Solubility | 2.4 g/L (20 ºC) |
| BRN | 2744 |
| Exposure limits | TLV-TWA 6 mg/m3 (1 ppm) (ACGIH); 1 ppm (15 min) (NIOSH). |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | FQYUMYWMJTYZTK-UHFFFAOYSA-N |
| LogP | 1.61 at 25℃ |
| CAS DataBase Reference | 122-60-1(CAS DataBase Reference) |
| IARC | 2B (Vol. 47, 71) 1999 |
| NIST Chemistry Reference | Oxirane, (phenoxymethyl)-(122-60-1) |
| EPA Substance Registry System | Phenyl glycidyl ether (122-60-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H317-H332-H335-H341-H350-H412 | |||||||||
| Precautionary statements | P202-P273-P280-P302+P352-P304+P340+P312-P308+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 45-20-37/38-43-52/53-68 | |||||||||
| Safety Statements | 53-45-61 | |||||||||
| OEL | Ceiling: 1 ppm (6 mg/m3) [15-minute] | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TZ3675000 | |||||||||
| Autoignition Temperature | 430 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29109000 | |||||||||
| Toxicity | LD50 orally in Rabbit: 2150 mg/kg LD50 dermal Rabbit 1500 mg/kg | |||||||||
| IDLA | 100 ppm | |||||||||
| NFPA 704 |
|
Glycidyl phenyl ether price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.20553 | 2,3-Epoxypropyl phenyl ether for synthesis | 122-60-1 | 250ML | ₹2860 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20553 | 2,3-Epoxypropyl phenyl ether for synthesis | 122-60-1 | 20KG | ₹74380.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 248487 | 1,2-Epoxy-3-phenoxypropane 99% | 122-60-1 | 50G | ₹2879.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 578576 | 1,2-Epoxy-3-phenoxypropane technical grade | 122-60-1 | 100G | ₹3095.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 248487 | 1,2-Epoxy-3-phenoxypropane 99% | 122-60-1 | 250G | ₹7079.55 | 2022-06-14 | Buy |
Glycidyl phenyl ether Chemical Properties,Uses,Production
Chemical Properties
Phenyl glycidyl ether, also known as glycidyl phenyl ether or PGE, is a clear liquid with a sweet odor that is considered unpleasant. It is soluble in ether and benzene, but insoluble in water. It has the ability to volatilize with water vapor. It is used in the production of epoxy resins, as a chemical intermediate, and as a stabilizer.
Uses
Phenyl glycidyl ether (PGE) is utilized in organic syntheses as an intermediate. As a reactive diluent, PGE is incorporated into uncured epoxy resins to lower viscosity, thereby facilitating casting, adhesives, and laminating applications.
Production Methods
PGE is synthesized by condensation of phenol with epichlorohydrin, with subsequent dehydrochlorination with caustic to form the epoxy ring.
General Description
Colorless liquid.
Air & Water Reactions
Ethers tend to form unstable peroxides when exposed to oxygen. Ethyl, isobutyl, ethyl tert-butyl, and ethyl tert-pentyl ether are particularly hazardous in this respect. Ether peroxides can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Slightly soluble in water.
Reactivity Profile
Glycidyl phenyl ether, an ether, can act as a base. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
Health Hazard
PGE is a toxic compound exhibiting moderate irritant action and carcinogenicity inanimals. Application of 0.25 mg resulted insevere eye irritation in rabbits, while 500 mgcaused moderate skin irritation over a periodof 24 hours. Prolonged or repeated contactcan cause moderate irritation and skin sensitization in humans.
The symptoms of its toxicity in animalswere depression of the central nervous system and paralysis of the respiratory tract.Prolonged exposure caused changes in thekidney, liver, thymus, and testes, and lossof hair in rats. The toxicity of this compound in humans is low and the health hazardcan arise primarily from its skin-sensitizationaction.
LD50 value, oral (mice): 1400 mg/kg
DGE showed carcinogenicity in rats, causingnasal cancer.
Fire Hazard
Glycidyl phenyl ether is probably combustible.
Contact allergens
This monoglycidyl derivative is a reactive diluent in epoxy resins Bisphenol A type. It is a component of epoxy paints, epoxy glues, and epoxy resins. Sensitization has been observed in many professions, such as in construction workers, marble workers, ceramic workers, and shoemakers.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion, skin contact, and subcutaneous routes. A severe eye and skin irritant. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used as a chemical intermediate. See also ETHERS
Potential Exposure
PGE is used to increase storage time and stability of halogenated compounds; as a reactive diluent in uncured epoxy resins to reduce the viscosity of the uncured system for ease in casting; adhesive, and laminating applications. NIOSH once estimated that 8000 workers are potentially exposed to PGE.
Carcinogenicity
Chronic exposure of rats to 1 or 12ppm 6 hours/day, 5 days/week for 2 years caused an increased incidence of rhinitis, squamous metaplasia, and epidermal carcinomas of the nasal cavity.4 The IARC has determined that there is sufficient evidence for the carcinogenicity of PGE in animals and that it is possibly carcinogenic to humans.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, amines, and curing agents. PGE can presumably form explosive peroxides
Waste Disposal
Concentrated waste containing no peroxides-discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxidesperforation of a container of the waste from a safe distance followed by open burning.
Glycidyl phenyl ether Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Srisyn Labs | +91-9705168728 +91-9705168728 | Hyderabad, India | 45 | 58 | Inquiry |
| Yuvraj Chemicals Pvt Ltd | 91-20-24338472 | Maharashtra, India | 15 | 58 | Inquiry |
| Pliogrip Resins & Chemicals Pvt Ltd. | +91 (25) 1287-1078 | New Delhi, India | 2 | 0 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| PURNIMA ENTERPRISE | 07942544503 | Ahmedabad, India | 4 | 58 | Inquiry |
| Sindhwani Traders India | 08048959147 | Delhi, India | 6 | 58 | Inquiry |
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