Propiophenone
- CAS No.
- 93-55-0
- Chemical Name:
- Propiophenone
- Synonyms
- 1-PHENYL-1-PROPANONE;phenylpropanone;1-phenyl-propan-1-one;Propiophenon;ETHYL PHENYL KETONE;FEMA 3469;usafek-1235;Propiophene;USAF ek-1235;phenylpropone
- CBNumber:
- CB8695754
- Molecular Formula:
- C9H10O
- Molecular Weight:
- 134.18
- MOL File:
- 93-55-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/27 15:07:49
| Melting point | 17-19 °C(lit.) |
|---|---|
| Boiling point | 218 °C(lit.) |
| Density | 1.009 g/mL at 25 °C(lit.) |
| vapor pressure | 1 mm Hg ( 50 °C) |
| refractive index |
n |
| FEMA | 3469 | PROPIOPHENONE |
| Flash point | 190 °F |
| storage temp. | Store below +30°C. |
| solubility | Insoluble in water, soluble in alcohol and oils |
| form | Liquid |
| color | Clear colorless to light yellow |
| Odor | at 10.00 % in dipropylene glycol. hawthorn lilac floral aromatic cherry herbal |
| Odor Type | floral |
| Water Solubility | INSOLUBLE |
| Merck | 14,7830 |
| JECFA Number | 824 |
| BRN | 606215 |
| Dielectric constant | 15.5 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong bases. |
| InChIKey | KRIOVPPHQSLHCZ-UHFFFAOYSA-N |
| LogP | 2.71 |
| CAS DataBase Reference | 93-55-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Propanone, 1-phenyl-(93-55-0) |
| EPA Substance Registry System | Propiophenone (93-55-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H227 | |||||||||
| Precautionary statements | P210e-P280a-P370+P378a-P403+P235-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UG7175000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2914 39 00 | |||||||||
| Toxicity | LD50 orally in Rabbit: 4490 mg/kg LD50 dermal Rabbit 4490 mg/kg | |||||||||
| NFPA 704 |
|
Propiophenone price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P51605 | Propiophenone 99% | 93-55-0 | 2G | ₹2024.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P51605 | Propiophenone 99% | 93-55-0 | 100G | ₹2035.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P51605 | Propiophenone 99% | 93-55-0 | 500G | ₹5076.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.07024 | Propiophenone for synthesis | 93-55-0 | 250ML | ₹4420 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.07024 | Propiophenone for synthesis | 93-55-0 | 1L | ₹10750 | 2022-06-14 | Buy |
Propiophenone Chemical Properties,Uses,Production
Chemical Properties
Propiophenone has a strong, flowery odor. 1-Phenyl-1-propanone is a colorless liquid with a flowery odor, insoluble in water, readily soluble in organic solvents. Typical reactions can be carried out at the methylene group, the carbonyl group, and at the aromatic nucleus.
Occurrence
Reported found in coffee, roasted filberts, roasted peanuts and roasted green tea. Also reported found in Camembert cheese, black tea, roasted macadamia nut, tamarind, dried bonito, cherimoya and sapodilla fruit.
Uses
Propiophenone is an aryl ketone used in the preparation of pharmaceutical and organic compounds. Propiophenone is used in perfumes as well as in the preparation of neurochemical compounds such as ephe drines.
Uses
1-Phenyl-1-propanone is used mainly as an intermediate for pharmaceuticals such as DPropoxyphen, phenylpropanolamine, and Phenmetrazine.
Production Methods
Propiophenone is produced by the Friedel–Crafts acylation of benzene with propionic acid chloride in the presence of aluminum chloride. It may also be produced by the reaction of benzoic acid and propionic acid using a calcium acetate– aluminum oxide catalyst.
Definition
ChEBI: Propiophenone is an aromatic ketone in which the two substituents on the carbonyl C atom are phenyl and ethyl. It has a role as a fragrance.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by subcutaneous route. Mildly toxic by ingestion and skin contact. A skin and eye irritant. A flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.
Propiophenone Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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