Chinese english Japanese Germany Korea

EIPA

EIPA Structure
CAS No.
1154-25-2
Chemical Name:
EIPA
Synonyms
ethylisopropylamiloride;EIPA;MH 12-43;L 593754;Ethylisopropylamiloride (EIPA);5-(N-ETHYL-N-ISOPROPYL)AMILORIDE;AMILORIDE, 5-(N-ETHYL-N-ISOPROPYL)-;Amiloride,5-(N-Ethyl-N-isopropyl)-[5-(N-Ethyl-N-isopropyl)amiloride;3-AMino-N-(aMinoiMinoMethyl)-6-chloro-5-[ethyl(1-Methylethyl)aMino]-;3-amino-6-chloro-N-(diaminomethylene)-5-[ethyl(isopropyl)amino]pyrazinamide
CBNumber:
CB1706411
Molecular Formula:
C11H18ClN7O
Molecular Weight:
299.76
MOL File:
1154-25-2.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

EIPA Properties

Melting point 202-205 °C(lit.)
Density 1.49±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Acetonitrile (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka 8.67±0.46(Predicted)
form Off-white to yellow solid.
color Pale Yellow to Green
Stability Unstable in methanol
CAS DataBase Reference 1154-25-2

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
RIDADR  2811
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
2 0

EIPA price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A3085 5-(N-Ethyl-N-isopropyl)amiloride 1154-25-2 25MG ₹23403.65 2022-06-14 Buy
Sigma-Aldrich(India) A3085 5-(N-Ethyl-N-isopropyl)amiloride 1154-25-2 100MG ₹75818.3 2022-06-14 Buy
Product number Packaging Price Buy
A3085 25MG ₹23403.65 Buy
A3085 100MG ₹75818.3 Buy

EIPA Chemical Properties,Uses,Production

Description

Sodium-hydrogen exchangers (NHE) are involved in maintaining sodium and pH balance in a variety of tissues. They are also known as sodium-hydrogen antiporters and solute carrier family 9 members. 5-(N-ethyl-N-isopropyl)-Amiloride (EIPA) is a potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and NHE5 with Ki values of 0.02, 0.5, 2.4, and 0.42 μM, respectively. It less effectively inhibits NHE4 (IC50 ≥10 μM). EIPA is commonly used at a concentration of 5-10 μM to inhibit cellular HNE activity.

Chemical Properties

Yellow Solid

EIPA Preparation Products And Raw materials

Raw materials

Preparation Products

EIPA Suppliers

Global( 101)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +8613735419629 China 9980 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
BOC Sciences 58
Career Henan Chemica Co 58
NewCan Biotech Limited 58
Alfa Chemistry 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
LEAPCHEM CO., LTD. 58
Shanghai Acmec Biochemical Technology Co., Ltd. 58
Aladdin Scientific 58

1154-25-2(EIPA)Related Search:

N-ethyl-pyrrolidone 2-amino-3-chloro-5-methyl-pyrazine 5-(N,N-HEXAMETHYLENE)-AMILORIDE 2-Chloro-6-methylpyrazine 2-Amino-5-chloropyrazine
AMILORIDE EIPA (PYRAZIN-2-YL)METHANAMINEHYDROCHLORIDE Pyrazinecarboxaldehyde, 5-(dimethylamino)- (9CI) 3-AMINO-N-METHYLPYRAZINE-2-CARBOXAMIDE
6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE 6-CHLORO-2-PYRAZINECARBOXAMIDE 2-pyrazinoylguanidine 5-AMINOPYRAZINE-2-CARBOXAMIDE 2-AMINO-3-CHLOROPYRAZINE
3-AMINO-6-CHLOROPYRAZINE-2-CARBALDEHYDE 2,6-Pyrazinediamine(9CI) 5-(N-Ethyl-N-isopropyl)amiloridehydrochloride
chevron_left

1of4

chevron_right
AMILORIDE, 5-(N-ETHYL-N-ISOPROPYL)- 5-(N-ETHYL-N-ISOPROPYL)AMILORIDE 3-AMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-5-[ETHYL(2-PROPYL)AMINO]-PYRAZINE-2-CARBOXAMIDE EIPA 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide L 593754 MH 12-43 3-Amino-5-(N-ethyl-N-isopropylamino)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide 3-Amino-5-[ethyl(isopropyl)amino]-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide 6-Chloro-3-amino-5-[ethyl(isopropyl)amino]-N-(diaminomethylene)-2-pyrazinecarboxamide 3-amino-6-chloro-N-(diaminomethylene)-5-[ethyl(isopropyl)amino]pyrazinamide 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide 3-azanyl-N-[bis(azanyl)methylidene]-6-chloro-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide 3-aMino-N-carbaMiMidoyl-6-chloro-5-(ethyl(isopropyl)aMino)pyrazine-2-carboxaMide 3-AMino-N-(aMinoiMinoMethyl)-6-chloro-5-[ethyl(1-Methylethyl)aMino]- Amiloride,5-(N-Ethyl-N-isopropyl)-[5-(N-Ethyl-N-isopropyl)amiloride Ethylisopropylamiloride (EIPA) 2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]- ethylisopropylamiloride 1154-25-2 C11H8ClN7O Cell Signaling and Neuroscience Cell Biology Amiloride and Derivatives BioChemical Monovalent Ion Channels Ion Channels Sodium Channel Modulators Voltage-gated Ion Channels All Inhibitors Bases & Related Reagents Inhibitors Intermediates & Fine Chemicals Nucleotides Pharmaceuticals