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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Apoptosis >Caspase activator >1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Structure
CAS No.
79183-19-0
Chemical Name:
1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE
Synonyms
CS-572;MDK83190;APOPTOSIS ACTIVATOR 2;APOPTOSIS ACTIVATOR II;MDK83190, 10 mM in DMSO;Apoptosis Activator 2, >=98%;1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE;1-[(3,4-DICHLOROPHENYL)METHYL]-1H-INDOLE-2,3-DIONE;1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]-;1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE USP/EP/BP
CBNumber:
CB1755989
Molecular Formula:
C15H9Cl2NO2
Molecular Weight:
306.14
MOL File:
79183-19-0.mol
MSDS File:
SDS
Modify Date:
2024/11/19 20:33:22
Request For Quotation

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Properties

Boiling point 470.6±55.0 °C(Predicted)
Density 1.494
Flash point 238.4℃
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Soluble in DMSO
form Orange to red solid.
pka -2.69±0.20(Predicted)
color Yellow to orange
Sensitive Light Sensitive

SAFETY

Risk and Safety Statements

Safety Statements  24/25
RIDADR  3077
HS Code  29145090

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Chemical Properties,Uses,Production

Uses

Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.

Biological Activity

Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC 50 = 4-9 μ M for leukaemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC 50 > 40 μ M).

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Suppliers

Global( 141)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 33024 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29858 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21142 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32202 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22854 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6391 58 Inquiry
Coresyn Pharmatech Co., Ltd. +86-571-86626709 +86-18157142896 China 9984 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Coresyn Pharmatech Co., Ltd. 58

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Spectrum

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE(79183-19-0)1HNMR

79183-19-0(1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE)Related Search:

N-METHYLISATIN Indole 1-ETHYL-1H-INDOLE-2,3-DIONE 1-(4-CHLORO-BENZYL)-1H-INDOLE-2,3-DIONE 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE
1-BENZYL-1H-INDOLE-2,3-DIONE 1-(2,6-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-OXIME 1-(2,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 1-(2,6-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 5-CHLORO-1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE
1-(2,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-[O-(2,4-DICHLOROBENZYL)OXIME] 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-OXIME 5-CHLORO-1-(2,6-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-[O-(2,6-DICHLOROBENZYL)OXIME] 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-[O-(4-CHLOROBENZYL)OXIME]
1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-(N-[2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYL]HYDRAZONE) 1-(2,6-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-[O-(2,6-DICHLOROBENZYL)OXIME] 1-(2,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-OXIME
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APOPTOSIS ACTIVATOR 2 APOPTOSIS ACTIVATOR II 1-[(3,4-DICHLOROPHENYL)METHYL]-1H-INDOLE-2,3-DIONE 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]- Apoptosis Activator 2, >=98% Apoptosis Activator 2, 97%, a cytochrome c caspase activator and apoptosis inducer CS-572 1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indole-2,3-dione MDK83190 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE USP/EP/BP Apoptosis Activator 2 (AAII), Cytochrome c caspase activator and apoptosis inducer 1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione/Apoptosis Activator 2 MDK83190, 10 mM in DMSO 79183-19-0 Inhibitors Caspases/Apoptosis