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dichlorisone

dichlorisone Structure
CAS No.
7008-26-6
Chemical Name:
dichlorisone
Synonyms
Disoderm;Diloderm;9,11β-Dichloro-17,21-dihydroxypregna-1,4-diene-3,20-dione;(11β)-9,11-Dichloro-17,21-dihydroxypregna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 9,11-dichloro-17,21-dihydroxy-, (11β)-;(8S,9R,10S,11S,13S,14S,17R)-9,11-dichloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CBNumber:
CB1932243
Molecular Formula:
C21H26Cl2O4
Molecular Weight:
413.34
MOL File:
7008-26-6.mol
Modify Date:
2023/5/15 10:43:56
Request For Quotation

dichlorisone Properties

Melting point 238-241 °C (decomp)(Solv: acetone (67-64-1))
alpha D20 +134° (pyridine)
Boiling point 586.4±50.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Pyridine (Slightly, Sonicated)
form Solid
pka 11.99±0.70(Predicted)
color White to Off-White

dichlorisone Chemical Properties,Uses,Production

Uses

Dichlorisone is a 9α,11β-dichloro corticoid. Dichlorisone has anti-antiinflammatory potency. Dichlorisone could be modifed to be used as glucocorticoid receptor agonists as well as a P-glycoprotein inhibitor.

dichlorisone Preparation Products And Raw materials

Raw materials

Triamcinolone acetonide 21-acetate N-Chlorosuccinimide

Preparation Products

dichlorisone Suppliers

Global( 7)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 China 10011 58 Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6088 71 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 96815 76 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56057 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Shaanxi Dideu Newmaterial Co., Ltd. 58
Toronto Research Chemicals 71
J & K SCIENTIFIC LTD. 76
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58

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9,11β-Dichloro-17,21-dihydroxypregna-1,4-diene-3,20-dione Diloderm Disoderm (11β)-9,11-Dichloro-17,21-dihydroxypregna-1,4-diene-3,20-dione Pregna-1,4-diene-3,20-dione, 9,11-dichloro-17,21-dihydroxy-, (11β)- (8S,9R,10S,11S,13S,14S,17R)-9,11-dichloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 7008-26-6 Intermediates & Fine Chemicals Pharmaceuticals Steroids