Pipequaline

Pipequaline Structure
CAS No.
77472-98-1
Chemical Name:
Pipequaline
Synonyms
PK-8165;45319RP;RP-45319;Pipequaline;CAS_77472-98-1;pipequaline PK-8165;PK-8165; PK8165; PK 8165;pipequaline HCI(PK-8165);pipequaline.HCl(for free base);2-phenyl-4-(2-piperidin-4-ylethyl)quinoline
CBNumber:
CB21179512
Molecular Formula:
C22H24N2
Molecular Weight:
316.44
MOL File:
77472-98-1.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:01

Pipequaline Properties

Boiling point 489.2±30.0 °C(Predicted)
Density 1.078±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 10 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml
form A crystalline solid
pka 10.60±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Pipequaline Chemical Properties,Uses,Production

Description

Pipequaline is a partial agonist of central benzodiazepine receptors (Ki = 78 nM in a radioligand binding assay). In mice, pipequaline enhances the effects of diazepam , further reducing foot shock-induced fighting behavior and the number of maximal electroshock-induced seizures and potentiating the muscle relaxant and hypnotic effects. Pipequaline also increases drinking in the Vogel punished drinking task indicating anxiolytic-like activity that can be reversed by the benzodiazepine receptor antagonist flumazenil .

Pipequaline Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 58)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29824 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
PT CHEM GROUP LIMITED China 35426 58 Inquiry
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 027-88013699 17354350817 China 7431 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20293 58 Inquiry
SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40067 58 Inquiry
Pipequaline 2-Phenyl-4-[2-(4-piperidinyl)ethyl]quinoline 45319RP PK-8165 RP-45319 pipequaline PK-8165 PK-8165; PK8165; PK 8165 2-phenyl-4-(2-piperidin-4-ylethyl)quinoline CAS_77472-98-1 pipequaline.HCl(for free base) pipequaline HCI(PK-8165) Quinoline, 2-phenyl-4-[2-(4-piperidinyl)ethyl]- 77472-98-1