illudin M

illudin M Structure
CAS No.
1146-04-9
Chemical Name:
illudin M
Synonyms
illudin M;(3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one;(3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one;(3'S,6'R)-3',6'-dihydroxy-2',2',4',6'-tetramethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-one;Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
CBNumber:
CB21385676
Molecular Formula:
C15H20O3
Molecular Weight:
248.32
MOL File:
1146-04-9.mol
Modify Date:
2024/11/19 15:53:33

illudin M Properties

Melting point 120-122.5° (Matsumoto); mp 128-130° (McMorris)
Boiling point 452.4±45.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A solid
pka 12.57±0.70(Predicted)
color Off-white to light yellow

illudin M Chemical Properties,Uses,Production

Description

Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies.

Uses

Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication.

illudin M Preparation Products And Raw materials

Raw materials

Preparation Products

illudin M Suppliers

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Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9976 58 Inquiry
illudin M (3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one (3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)- (3'S,6'R)-3',6'-dihydroxy-2',2',4',6'-tetramethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-one 1146-04-9 ADC