5-Chloro-1-indanone
- CAS No.
- 42348-86-7
- Chemical Name:
- 5-Chloro-1-indanone
- Synonyms
- 5-Chloro-2,3-dihydro-1H-inden-1-one;Chloro-1-indan;5-Chloro Indanone;5- chlorineindone;5-CHLORO-1-INDANONE;5-CHLOROINDAN-1-ONE;1-Indanone, 5-chloro-;5-Chloro-1-indanone,99%;5-Chloro-1-indanone,98%;5-Chloro-1-indanone >
- CBNumber:
- CB2148511
- Molecular Formula:
- C9H7ClO
- Molecular Weight:
- 166.6
- MOL File:
- 42348-86-7.mol
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 94-98 °C (lit.) |
|---|---|
| Boiling point | 124-125 °C (3 mmHg) |
| Density | 1.1466 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| Flash point | 124-125°C/3mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Solid |
| color | Light Beige to Beige |
| Water Solubility | insoluble |
| BRN | 1448000 |
| InChIKey | MEDSHTHCZIOVPU-UHFFFAOYSA-N |
| CAS DataBase Reference | 42348-86-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Chloro-1-indanone(42348-86-7) |
| EPA Substance Registry System | 1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
5-Chloro-1-indanone price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 433071 | 5-Chloro-1-indanone 99% | 42348-86-7 | 5G | ₹13953.43 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C1644 | 5-Chloro-1-indanone min. 97.0 % | 42348-86-7 | 1G | ₹3600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C1644 | 5-Chloro-1-indanone min. 97.0 % | 42348-86-7 | 5G | ₹13000 | 2022-05-26 | Buy |
| ottokemi | C 8067 | 5-Chloro-1-indanone, 99% | 42348-86-7 | 5gm | ₹12006 | 2022-05-26 | Buy |
| ottokemi | C 8067 | 5-Chloro-1-indanone, 99% | 42348-86-7 | 25gm | ₹24039 | 2022-05-26 | Buy |
5-Chloro-1-indanone Chemical Properties,Uses,Production
Chemical Properties
White Crystal
Uses
5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors.
Preparation
3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone
General Description
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BTC pharm India | +918790379245 | AndhraPradesh, India | 1262 | 58 | Inquiry |
| ARRKEM LIFE SCIENCES PRIVATE LIMITED | +91-8148739767 +91-8148739767 | Telangana, India | 347 | 58 | Inquiry |
| Chemphora life sciences | +91-9849979989 +91-9849979989 | Hyderabad, India | 326 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Chempure | 08047626574 | Mumbai, India | 144 | 58 | Inquiry |
| Brisben Chemicals | 08048963750 | Mumbai, India | 508 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6202 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| BTC pharm India | 58 |
| ARRKEM LIFE SCIENCES PRIVATE LIMITED | 58 |
| Chemphora life sciences | 58 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Chempure | 58 |
| Brisben Chemicals | 58 |
| CHEMSWORTH | 30 |
| OCEAN TRADING CORPORATION | 58 |
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