ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

CAS No.: 27470-51-5

Chemical Name:: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

Synonyms: ae-17;flogos;alfide;solurol;Aflogan;Calibene;SUXIBUZONE;Suxibuzona;lidinedione;Suxibuzonum

CBNumber:: CB2196749

Molecular Formula:: C24H26N2O6

Molecular Weight:: 438.47

MOL File:: 27470-51-5.mol

Modify Date:: 2024/7/2 8:55:03

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4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Properties

Melting point	126-127°
Boiling point	550.33°C (rough estimate)
Density	1.2847 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	2-8°C
solubility	Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
form	Solid
pka	4.33±0.17(Predicted)
color	White to Off-White
CAS DataBase Reference	27470-51-5

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332
Precautionary statements	P261-P280-P301+P312+P330
Hazard Codes	Xn
Risk Statements	20/21/22
Safety Statements	36
WGK Germany	3
RTECS	WM9640000
Toxicity	LD50 orally in mice: 5.683 micromol/kg (Esteve, 1973)

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

analgesic, antipyretic, antiinflammatory

Definition

ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.

World Health Organization (WHO)

Suxibuzone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1974 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone.

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Preparation Products And Raw materials

Raw materials

Preparation Products

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Suppliers

Global( 83)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	China	9991	58	Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD	+86-0512-83500002 +8615195660023	China	23053	58	Inquiry
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	United States	19639	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Nextpeptide Inc	58
Coresyn Pharmatech Co., Ltd.	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	58
Aceschem Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

27470-51-5(4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER])Related Search:

3-METHOXYPROPIONIC ACID HYDRAZIDE 4,4-Dimethyl-1-phenyl-3-pyrazolidone 1-Acetyl-2-phenylhydrazine MOFEBUTAZONE 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

Dimezone S 3-AMINO-2,2-DIMETHYL-1-PROPANOL 1,2-Diphenylhydrazine Phenylbutazone Phenidone

1-Phenyl-4-methyl-3-pyrazolidone 2,2-Dimethylpropionic acid hydrazide 1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE 2,2,2-TRIMETHYLACETANILIDE 3-METHOXY-2,2-DIMETHYLPROPYLAMINE

MALONANILIDE N-PHENYL-N'-PROPIONYLHYDRAZINE 2,2-dimethyl-3-(methylamino)propan-1-ol

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4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 4-butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedio 4-butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedionehydrogensuccinate ae-17 alfide SUXIBUZONE butanedioicacid,mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl flogos lidinedione solurol succinicacid,monoesterwith4-butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazo 3-(1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine-4-ylmethoxycarbonyl)propionic acid Succinic acid hydrogen (1,2-diphenyl-3,5-dioxo-4-butylpyrazolidin-4-yl)methyl ester Succinic acid hydrogen (4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl ester Succinic acid hydrogen 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester 3-((4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxycarbonyl)propionsaeure 3,5-Pyrazolidinedione, 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-, hydrogen succinate (ester) 4-Butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione 4-Hydroxymethylbutazolidine hemisuccinate Aflogan Acetanilide Impurity 1 Suxibuzone CRS Butanedioic acid, 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester 4-((4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy)-4-oxobutanoic acid Calibene Suxibuzona Suxibuzonum Inhibitor,Suxibuzone,inhibit 1-[3-[2-(dimethylamino)ethyl]-1-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfon amide 27470-51-5 Biochemicals and Reagents BioChemical Substrate Analogs Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Enzyme Inhibitors DANILON