5,5′-Dithiobis(2-nitrobenzoic acid)

- CAS No.
- 69-78-3
- Chemical Name:
- 5,5′-Dithiobis(2-nitrobenzoic acid)
- Synonyms
- DTNB;Ba-2767;5,5'Ellmanns;5,5&priMe;Ellmsn'sreagent;ELLMANS' REAGENT;ELLMAN'S REAGENT;ellmann's reagent;SAPONIN BIOCHEMICAL
- CBNumber:
- CB2215444
- Molecular Formula:
- C14H8N2O8S2
- Molecular Weight:
- 396.35
- MOL File:
- 69-78-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/2/14 13:52:13
Melting point | 240-245 °C (dec.)(lit.) |
---|---|
Boiling point | 671.9±55.0 °C(Predicted) |
bulk density | 290kg/m3 |
Density | 1.67 |
refractive index | 1.6900 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | ethanol: 8mg/mL |
pka | 1.57±0.25(Predicted) |
form | Yellow solid |
color | Pale Yellow to Light Yellow |
Water Solubility | Soluble in water and ethanol. |
Merck | 14,3551 |
BRN | 1896821 |
Stability | Stable. Incompatible with strong bases, strong oxidizing agents. |
InChIKey | KIUMMUBSPKGMOY-UHFFFAOYSA-N |
CAS DataBase Reference | 69-78-3(CAS DataBase Reference) |
EPA Substance Registry System | Benzoic acid, 3,3'-dithiobis[6-nitro- (69-78-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DG9650000 | |||||||||
F | 10 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29309070 | |||||||||
NFPA 704 |
|
5,5′-Dithiobis(2-nitrobenzoic acid) price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D8130 | 5,5′-Dithiobis(2-nitrobenzoic acid) ≥98%, BioReagent, suitable for determination of sulfhydryl groups | 69-78-3 | 500MG | ₹2200 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D8130 | 5,5′-Dithiobis(2-nitrobenzoic acid) ≥98%, BioReagent, suitable for determination of sulfhydryl groups | 69-78-3 | 1G | ₹3970 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D8130 | 5,5′-Dithiobis(2-nitrobenzoic acid) ≥98%, BioReagent, suitable for determination of sulfhydryl groups | 69-78-3 | 5G | ₹9660 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D8130 | 5,5′-Dithiobis(2-nitrobenzoic acid) ≥98%, BioReagent, suitable for determination of sulfhydryl groups | 69-78-3 | 10G | ₹17820 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D8130 | 5,5′-Dithiobis(2-nitrobenzoic acid) ≥98%, BioReagent, suitable for determination of sulfhydryl groups | 69-78-3 | 25G | ₹24258.83 | 2022-06-14 | Buy |
5,5′-Dithiobis(2-nitrobenzoic acid) Chemical Properties,Uses,Production
Chemical Properties
Crystalline
Uses
5,5′-Dithiobis(2-nitrobenzoic acid) is a water soluble reagent mainly used for the derivatization of sulfhydryl groups.
Definition
ChEBI: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.
General Description
5,5′-Dithiobis(2-nitrobenzoic acid) is also called DTNB or Ellman′s reagent. It is a water soluble reagent, which interacts with thiol groups, and can be used conveniently at neutral pH. Thiolate anion (RS-) reacts with Ellman′s reagent (DTNB2-), to produce 2-nitro-5-thiobenzoate anion (TNB2-) and one mixed disulfide (R-S-TNB-). TNB2- has a high molar absorption coefficient, and absorbs at 412nm. This absorption is independent of pH, at pH> 7.3.
5,5′-Dithiobis(2-nitrobenzoic acid) Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6905 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
Innovative | 07942565925 | Mumbai, India | 617 | 58 | Inquiry |
Global Chemie | 08046043260 | Mumbai, India | 162 | 58 | Inquiry |
Supplier | Advantage |
---|---|
CHEMSWORTH | 30 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
Otto Chemie Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
Triveni chemicals | 58 |
Central Drug House(P) Ltd. | 58 |
Innovative | 58 |
Global Chemie | 58 |
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- Uses of 5,5'-Dithiobis(2-nitrobenzoic acid)
- 5,5'-Dithiobis(2-nitrobenzoic acid) (DTNB)is an organic disulfide that results from the formal oxidative dimerisation of 2-nit....
- Nov 1,2019
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