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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Structure
CAS No.
1384441-38-6
Chemical Name:
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Synonyms
O-Demethyl apremilast;Apremilast Impurity K;Apremilast O-Desmethyl;O-Desmethyl Apremilast;Apremilast impurity HS093311;Apremilast Impurity 4 (O-Desmethyl Apremilast);N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide;N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide;Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-;(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity
CBNumber:
CB23145520
Molecular Formula:
C21H22N2O7S
Molecular Weight:
446.47
MOL File:
1384441-38-6.mol
Modify Date:
2024/6/6 17:55:34
Request For Quotation

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Properties

Boiling point 765.2±60.0 °C(Predicted)
Density 1.450±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
form A crystalline solid
pka 9.80±0.31(Predicted)
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Chemical Properties,Uses,Production

Uses

N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide is a related compound of Apremilast (A729700), which is?an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide may be a useful compound for determining metabolic clearance of apremilast. Apremilast Impurity 7

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Suppliers

Global( 45)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23555 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD +8618627948422 China 3389 58 Inquiry
Hubei Moco Chemical Co., Ltd. 18576690171 China 10993 58 Inquiry
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 0086-15250997978 China 7786 55 Inquiry
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657 China 4920 58 Inquiry
Hunan Zengda Biological Technology Co., LTD 18711085600 China 4583 58 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
CLEARSYNTH LABS LTD. 58
ANHUI WITOP BIOTECH CO., LTD 58
LEAP CHEM CO., LTD. 58
China National Standard Pharmaceutical Corporation Limited 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 58
Hubei Moco Chemical Co., Ltd. 58
Nanjing XiZe Biotechnology CO., Ltd. 55
Beijing Comparison Pharmaceutical Technology Co., Ltd 58
Hunan Zengda Biological Technology Co., LTD 58

1384441-38-6((S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide)Related Search:

1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone Apremilast Apremilast (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide APST-ZA
Apremilast Impurity E Apremilast Impurity 1 Apremilast (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Apremilast Impurity 1/2
Apremilast Impurity 8 Apremilast Impurity 13 Apremilast Impurity 28 Apremilast Impurity 25 Apremilast-d8
3-acetamidophthalic acid Apremilast Impurity 2 Apremilast Impurity 9
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O-Desmethyl Apremilast N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide Apremilast impurity HS093311 Apremilast Impurity K Apremilast Impurity 4 (O-Desmethyl Apremilast) Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl- N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity O-Demethyl apremilast Apremilast O-Desmethyl 1384441-38-6