ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
![(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Structure](CAS/20180702/GIF/1384441-38-6.gif)
- CAS No.
- 1384441-38-6
- Chemical Name:
- (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
- Synonyms
- O-Demethyl apremilast;Apremilast Impurity K;Apremilast O-Desmethyl;O-Desmethyl Apremilast;Apremilast impurity HS093311;Apremilast Impurity 4 (O-Desmethyl Apremilast);N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide;N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide;Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-;(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity
- CBNumber:
- CB23145520
- Molecular Formula:
- C21H22N2O7S
- Molecular Weight:
- 446.47
- MOL File:
- 1384441-38-6.mol
- Modify Date:
- 2024/6/6 17:55:34
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Properties
Boiling point | 765.2±60.0 °C(Predicted) |
---|---|
Density | 1.450±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml |
form | A crystalline solid |
pka | 9.80±0.31(Predicted) |
Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
NFPA 704 |
|
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Chemical Properties,Uses,Production
Uses
N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide is a related compound of Apremilast (A729700), which is?an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide may be a useful compound for determining metabolic clearance of apremilast. Apremilast Impurity 7
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 45)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23555 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11927 | 58 | Inquiry |
ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | China | 3389 | 58 | Inquiry |
Hubei Moco Chemical Co., Ltd. | 18576690171 | China | 10993 | 58 | Inquiry |
Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 0086-15250997978 | China | 7786 | 55 | Inquiry |
Beijing Comparison Pharmaceutical Technology Co., Ltd | 010-010-52878169 15801002657 | China | 4920 | 58 | Inquiry |
Hunan Zengda Biological Technology Co., LTD | 18711085600 | China | 4583 | 58 | Inquiry |
1384441-38-6((S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide)Related Search:
1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone
Apremilast
Apremilast
(S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
APST-ZA
Apremilast Impurity E
Apremilast Impurity 1
Apremilast
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt
Apremilast Impurity 1/2
chevron_left
1of4
chevron_right
O-Desmethyl Apremilast
N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
Apremilast impurity HS093311
Apremilast Impurity K
Apremilast Impurity 4 (O-Desmethyl Apremilast)
Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-
N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide
(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity
O-Demethyl apremilast
Apremilast O-Desmethyl
1384441-38-6