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COUMESTROL

CAS No.: 479-13-0

Chemical Name:: COUMESTROL

Synonyms: Nsc22842;Cumostrol;Cumoestrol;COUMESTROL;COUMOESTROL;cumoesterol;Coumesterol;COUMESTROL(P);Coumestrol,99%;Coumestrol, >98%

CBNumber:: CB2339816

Molecular Formula:: C15H8O5

Molecular Weight:: 268.22

MOL File:: 479-13-0.mol

Modify Date:: 2023/9/4 15:51:00

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COUMESTROL Properties

Melting point	≥350 °C(lit.)
Boiling point	331.39°C (rough estimate)
Density	1.2586 (rough estimate)
refractive index	1.7680 (estimate)
storage temp.	Refrigerator
solubility	DMSO: soluble
form	Light beige solid.
pka	8.25±0.20(Predicted)
color	Pale Yellow to Dark Brown
BRN	266702
LogP	2.940 (est)
CAS DataBase Reference	479-13-0(CAS DataBase Reference)
EPA Substance Registry System	Coumestrol (479-13-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

22-36/37/38

Safety Statements

26-36

WGK Germany

RTECS

DF8077000

NFPA 704

	0
2		0

COUMESTROL price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	27883	Coumestrol BioReagent, suitable for fluorescence, ≥97.5% (HPLC)	479-13-0	1MG	₹4557.33	2022-06-14	Buy
Sigma-Aldrich(India)	27885	Coumestrol ≥95.0% (HPLC)	479-13-0	50MG	₹19950.48	2022-06-14	Buy
Sigma-Aldrich(India)	27883	Coumestrol BioReagent, suitable for fluorescence, ≥97.5% (HPLC)	479-13-0	5MG	₹17872.08	2022-06-14	Buy

Product number	Packaging	Price	Buy
27883	1MG	₹4557.33	Buy
27885	50MG	₹19950.48	Buy
27883	5MG	₹17872.08	Buy

COUMESTROL Chemical Properties,Uses,Production

Description

Coumestrol is a phytoestrogen that occurs naturally in soybeans, spinach, and clover. It competitively (vs. 17β-estradiol, ) binds the estrogen receptors ERα (IC₅₀ = 11 nM) and ERβ (IC₅₀ = 2 nM) and can induce ER-dependent gene expression in isolated cells. Coumestrol is also a weak antagonist of pregnane X receptor (IC₅₀ = 12 μM) as well as a potential inverse agonist of the constitutive androstane receptor (EC₅₀ = 30 μM).

Chemical Properties

Yellow to Beige Powder

Definition

ChEBI: A member of the class of coumestans that is coumestan with hydroxy substituents at positions 3 and 9.

Safety Profile

An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

COUMESTROL Preparation Products And Raw materials

Raw materials

Preparation Products

COUMESTROL Suppliers

Global( 149)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Biosyn Research Chemicals	+91-91-9346022300 +91-9346022300	Telangana, India	465	58	Inquiry
chakrachem Lifesciences	+91 9902744663	Hyderabad, India	451	58	Inquiry
Neugen Labs	+91-8133254502 +91-8133254502	Karnataka, India	195	58	Inquiry
Biosyn Research Chemicals	+91 9346022300/+91 9399339999	Telangana, India	1340	58	Inquiry
A. B. Enterprises	+91-8048077585	Mumbai, India	1396	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29899	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-15319487004	China	2130	58	Inquiry
Finetech Industry Limited	+86-27-87465837 +8618971612321	China	9640	58	Inquiry
sgtlifesciences pvt ltd	+8617013299288	China	12382	58	Inquiry

Supplier	Advantage
Biosyn Research Chemicals	58
chakrachem Lifesciences	58
Neugen Labs	58
Biosyn Research Chemicals	58
A. B. Enterprises	58
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Finetech Industry Limited	58
sgtlifesciences pvt ltd	58

COUMESTROL Spectrum

COUMESTROL(479-13-0)¹HNMR

479-13-0(COUMESTROL)Related Search:

BAVACHININ A 8-Prenyldaidzein 1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol WEDELOLACTONE

psoralidin 3-HYDROXY-8,9-METHYLENEDIOXYCOUMESTAN COUMESTROL demethylwedelolactone 3-HYDROXY-9-METHOXYCOUMESTAN

neoglycyrol COUMESTROL DIMETHYL ETHER,COUMESTROL DIMETHYL ETHER, FOR FLUORESCE 4'-ORTHO-METHYL-COUMESTROL COUMESTROL DIACETATE MEDICAGO COUMESTROL 10%

COUMESTROL(RG) COUMESTROL DIACETATE, FOR FLUORESCENCE* TRIFOLIOL

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cumoesterol COUMOESTROL 7 12-DIHYDROXYCOUMESTAN 98% Coumesterol COUMESTROL(P) 2-(2 4-DIHYDROXYPHENYL)-6-HYDROXY-3-BENZOFURANCARBOXYLIC ACID D-LACTONE 98% Coumestrol,99% 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone 6H-Benzofuro[3,2-C][1]benzopyran-6-one, 3,9-dihydroxy- Cumoestrol Cumostrol Nsc22842 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic Acid δ-Lactone 7,12-DIHYDROXYCOUMESTAN 7,12-DIHYDROXYCOUMESTANE 7(1), 6-DIHYDROXYCOUMARINO(3(1), 4(1), 3,2)COUMARONE [2-(2,4-DIHYDROXYPHENYL)-6-HYDROXY-3-BENZOFURAN-CARBOXYLIC ACID ALPHA-LACTONE] 2-(2,4-DIHYDROXYPHENYL)-6-HYDROXY-3-BENZOFURANCARBOXYLIC ACID DELTA-LACTONE 2-(2 4-DIHYDROXYPHENYL)-6-HYDROXY-3-BENZOFURANCARBOXYLIC ACID D-LACTONE COUMESTROL COUMESTROL BIOREAGENT, SUITABLE FOR 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one 3,9-DIHYDROXY-6H-BENZOFURO[3,2-C]-[1]BENZOPYRAN-6-ONE 2-(2,4-dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylicacidelta-lacton 2-c)(1)benzopyran-6-one,3,9-dihydroxy-6h-benzofuro( 2-c][1]benzopyran-6-one,3,9-dihydroxy-6h-benzofuro[ Coumestrol, >98% 3,9-dihydroxy-6-benzofuro[3,2-c][1]benzopyranone Coumestrol ( synthitic) 7’, 6-DIHYDROXYCOUMARINO(3’, 4’, 3, 2)COUMARONE 3,9-Dihydroxy-6H-benzofuro[3,2-c]chromen-6-one Coumestrol (Synthetic) 5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.02,?.011,1?]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaen-9-one 479-13-0 C15H9O5 C15H8O5 Steroids & Hormones - 13C & 2H Steroids Coumarins Iso-Flavones