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PICROTIN

PICROTIN Structure
CAS No.
21416-53-5
Chemical Name:
PICROTIN
Synonyms
PICROTIN;Picrotin CRS;(1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-Hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione;3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-;(1aR,8aS,9S)-1aβ,2,2a,6,6aα,8b-Hexahydro-2aα-hydroxy-9-(1-hydroxy-1-methylethyl)-8bα-methyl-3α,6α-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione
CBNumber:
CB2383778
Molecular Formula:
C15H18O7
Molecular Weight:
310.3
MOL File:
21416-53-5.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03
Request For Quotation

PICROTIN Properties

Melting point 256-258°C
alpha D -64.7° (c = 2.31 in abs alc)
Boiling point 595.8±50.0 °C(Predicted)
Density 1.59
storage temp. 2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml
pka 13.28±0.60(Predicted)
form Solid
color White to off-white
EPA Substance Registry System Picrotin (21416-53-5)

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  TJ8800000
Toxicity LD50 i.p. in mice: 135 mg/kg (Jarboe)

PICROTIN Chemical Properties,Uses,Production

Description

Picrotin is a natural picrotoxane that antagonizes glycine receptors (GlyRs; IC50s = 57 and 117 μM for α1 and α2 homodimeric GlyRs, respectively). It also inhibits α3 homodimeric GlyRs. Picrotin is inactive in inhibiting γ-aminobutyric acid (GABA) type A and type C receptors. Picrotin occurs in the natural plant-derived poison picrotoxin , equimolar with picrotoxinin.

Uses

GABAa receptor antagonist

PICROTIN Preparation Products And Raw materials

Raw materials

Preparation Products

PICROTIN Suppliers

Global( 70)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Biosyn Research Chemicals +91 9346022300/+91 9399339999 Telangana, India 1340 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
ABCR GmbH & CO. KG 49 721 95061 0 Germany 6846 75 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
SHANGHAI ZZBIO CO., LTD. 18019219489 19921389125 China 12064 58 Inquiry
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 China 7059 55 Inquiry
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 China 12664 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24016 58 Inquiry
Supplier Advantage
Biosyn Research Chemicals 58
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
ABCR GmbH & CO. KG 75
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
SHANGHAI ZZBIO CO., LTD. 58
Wuhan ChemFaces Biochemical Co., Ltd. 55
Foshan Treasure Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58

PICROTIN Spectrum

PICROTIN(21416-53-5)1HNMR

21416-53-5(PICROTIN)Related Search:

PICROTIN (R)-5-Hydroxymethyldihydrofuran-2-one ETHYL N-HEPTYLOXYACETATE 3-HEPTYLDIHYDRO-5-METHYL-2(3H)-FURANONE ETHYL TETRAHYDROPYRAN-4-YL-ACETATE
cis-4-Hydroxycyclohexanecarboxylic acid Tetrahydropyranyl-4-acetic acid ε-Caprolactone D-(-)-PANTOLACTONE 4-METHOXYCYCLOHEXANECARBOXYLIC ACID
TETRAHYDROFURFURYL BUTYRATE Undecanedioic acid DL-Pantolactone Molecular complex (1:1) of picrotin and picrotoxinin,picrotin,compd.withpicrotoxinin(1:1 TRANS-P-MENTHANE-3,8-DIOL
METHYL 2-METHYLGLYCIDATE 2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER 6-OXABICYCLO[3.2.1]OCTAN-7-ONE
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PICROTIN (1aR,8aS,9S)-1aβ,2,2a,6,6aα,8b-Hexahydro-2aα-hydroxy-9-(1-hydroxy-1-methylethyl)-8bα-methyl-3α,6α-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-Hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione Picrotin CRS 3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)- 21416-53-5 C15H18O7 Analytical Standards Analytical Chromatography Product Catalog Alphabetic PEM - POLA Plant Oils, Toxins, Phenolic Acids & Derivatives