CAERULEIN
- CAS No.
- 17650-98-5
- Chemical Name:
- CAERULEIN
- Synonyms
- CERULETIDE;CERULEIN;FI-6934;Ceosunin;CAERULEIN;Caerulein (~90%);Ceruletide, >99%;CAERULEIN 500 UG;CAERULEIN SULFATED;CAERULEIN USP/EP/BP
- CBNumber:
- CB2384634
- Molecular Formula:
- C58H73N13O21S2
- Molecular Weight:
- 1352.4
- MOL File:
- 17650-98-5.mol
- Modify Date:
- 2023/9/28 17:55:30
Melting point | 224-226° (dec) |
---|---|
alpha | D20 -26° (c = 1 in DMF) |
Density | 1.464±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | 0.05 M ammonium hydroxide: 1 mg/mL, clear, colorless |
pka | -4.17±0.18(Predicted) |
form | Solid |
color | White to Off-White |
Water Solubility | Soluble to 1 mg/ml in water |
Merck | 13,2015 |
BRN | 5422487 |
InChIKey | YRALAIOMGQZKOW-HYAOXDFASA-N |
CAERULEIN Chemical Properties,Uses,Production
Uses
Caerulein is a ten amino acid oligopeptide that stimulates smooth muscle and increases digestive secretions. It is similar in action and composition to cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. It is used to induce pancreatitis in experimental animal models.
Definition
ChEBI: A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointes inal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.
Hazard
A poison.
Safety Profile
A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx
CAERULEIN Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 999 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12459 | 58 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16220 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10259 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Shanghai Longyu Biotechnology Co., Ltd. | +8613917842738 | China | 2534 | 58 | Inquiry |
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