ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Standard Substance >Ascomycin

Ascomycin

Ascomycin Structure
CAS No.
104987-12-4
Chemical Name:
Ascomycin
Synonyms
AAG;IMMUNOMYCIN;AscoMycin solution;Tacrolimus USP Related Compound A;CBR02;FK-520;FR 520;C058028;CS-1818;L 683590
CBNumber:
CB2406330
Molecular Formula:
C43H69NO12
Molecular Weight:
792.01
MOL File:
104987-12-4.mol
Modify Date:
2024/11/15 19:19:13

Ascomycin Properties

Melting point 153-157°C
Boiling point 868℃
Density 1.19±0.1 g/cm3(Predicted)
Flash point >110°(230°F)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility ≥38.9 mg/mL in DMSO; insoluble in H2O; ≥98.6 mg/mL in EtOH
form Powder
pka 9.97±0.70(Predicted)
color White to off-white
Water Solubility Soluble in DMSO at 65mg/ml; soluble in ethanol at 50mg/m; with warming. Very poorly soluble in water
InChIKey ZDQSOHOQTUFQEM-AMASXYNMSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H332-H319-H302-H312-H332
Precautionary statements  P210-P305+P351+P338-P261-P280h-P301+P312a-P304+P340-P321-P501a
Hazard Codes  Xn,F
Risk Statements  20/21/22-36-11
Safety Statements  36/37-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS  KD4185000
10
HS Code  29419090
NFPA 704
0
3 0

Ascomycin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A3835 Ascomycin from Streptomyces hygroscopicus var. ascomyceticus 104987-12-4 1MG ₹27679.53 2022-06-14 Buy
Sigma-Aldrich(India) A-094 Ascomycin solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 104987-12-4 1ML ₹26240.9 2022-06-14 Buy
Product number Packaging Price Buy
A3835 1MG ₹27679.53 Buy
A-094 1ML ₹26240.9 Buy

Ascomycin Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Ascomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1988. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant.

Definition

ChEBI: A macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties.

Ascomycin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 279)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Clickchem Research LLP +91-8140031133 +91-8140031133 Gujarat, India 411 58 Inquiry
Allmpus Laboratories Pvt Ltd +91-9518738415 +91-9167862134 Maharashtra, India 657 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Indogulf Group 91-22-23455220 Maharashtra, India 249 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
Maas Pharma Chemicals +91-9958666224 Delhi, India 1607 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6754 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3887 58 Inquiry

Ascomycin Spectrum

15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetram C058028 L 683590, FR 900520, IMMunoMycin, FK 520, WS 7238A, NSC 106410 Ascomycin:Tacrolimus Desmethylene Impurit Tacrolimus USP RC A FK-520 FR-900520 ASCOMYCIN, STREPTOMYCES HYGROSCOPICUS ASCOMYCIN, STREPTOMYCES HYGROSCOPICUS VAR ASCOMYCETICUS 12,18-tetramethyl-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,19s*,26ar*))--10 8-ethyl-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy ASCOMYCIN FROM STREPTOMYCESHYGROSCOPICUS VAR ASCOM Changchuanmycin FR 520 L 683590 15,19-Epoxy-3H-pyrido2,1-c1,4oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(1E)-2-(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl-1-methylethenyl-14,16-dimethoxy-4,10,12,18-te ascomycin from streptomyces hygroscopicus var. ascomyceticus Ascomycin Tacrolimus Imprity 6 Ascomycin:Tacrolimus Desmethylene Impurity Pimecrolimus 4-Deschloro-4-Hydroxy Impurity Tacrolimus impurity 2/Tacrolimus Related Compound A(USP)/Ascomycin/(3S,4R,5S, 8R,9E,12S, 14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24, 25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-1 TACROLIMUS RELATED COMPOUND A (ASCOMYCIN) Ascomycin(Immunomycin, FR-900520, FK520) CS-1818 FK520;FK 520 Ascomycin (Tacrolimus Related Compound A) Tacrolimus Impurity 5(Ascomycin)(Tacrolimus EP Impurity A)(Tacrolimus USP RC A) CBR02 Tacrolimus Desmethylene Impurity Ascorbic acid (tacrolimus-related compound A) 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4R,5S,8R,9E,12S,14S,1... Tacrolimus EP Impurity A US-DMF No.: 029433 AscomycinQ: What is Ascomycin Q: What is the CAS Number of Ascomycin Q: What is the storage condition of Ascomycin Q: What are the applications of Ascomycin AscoMycin solution Tacrolimus USP Related Compound A IMMUNOMYCIN AAG ChangChuan drug TacrolimusUSPRCA/Ascomycin comycin(FK 520) AUF4U5NSJK nagakuamycin TACROLIMUS EP IMP A Pimecrolimus 4-Hydroxy Analog ASCOMYCIN STANDARD Ascomycin (Tacrolimus EP Impurity A) Ascomycin impurity A 104987-12-4 104978-12-4 C43H69NO12 Antibiotics A to Z Antibiotics A-F Antibiotics BioChemical antibiotic Inhibitors