D(-)-Arginine
- CAS No.
- 157-06-2
- Chemical Name:
- D(-)-Arginine
- Synonyms
- D-ARGININE;H-D-ARG-OH;D-ARG;D-Arg-OH;D-Arginin;H-D-Arginine;ARGININE, D-;R-(-)-ARGININE;D-(-)-ARGININE;D-Arginine，98%
- CBNumber:
- CB2408147
- Molecular Formula:
- C6H14N4O2
- Molecular Weight:
- 174.2
- MOL File:
- 157-06-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/3 14:46:32
| Melting point | 226 °C (dec.) (lit.) |
|---|---|
| alpha | -28.5 º (c=8, 6 N HCl) |
| Boiling point | 305.18°C (rough estimate) |
| Density | 1.2297 (rough estimate) |
| refractive index | -23 ° (C=8, 6mol/L HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.49±0.24(Predicted) |
| color | White to Off-White |
| Water Solubility | SOLUBLE |
| Sensitive | Air Sensitive |
| BRN | 1725412 |
| InChIKey | ODKSFYDXXFIFQN-SCSAIBSYSA-N |
| LogP | -0.999 (est) |
| CAS DataBase Reference | 157-06-2(CAS DataBase Reference) |
| EPA Substance Registry System | D-Arginine (157-06-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280i-P337+P313-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CF1934220 | |||||||||
| F | 9 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29252000 | |||||||||
| NFPA 704 |
|
D(-)-Arginine price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 250MG | ₹2771.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 1G | ₹5185.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 5G | ₹19225.2 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A1029 | D-(-)-Arginine | 157-06-2 | 1G | ₹2800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A1029 | D-(-)-Arginine | 157-06-2 | 5G | ₹9800 | 2022-05-26 | Buy |
D(-)-Arginine Chemical Properties,Uses,Production
Description
D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine.
Chemical Properties
white to light yellow crystal powde
Uses
Arginine is an essential amino acid found in food and plant sources, and many biological systems.
D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man.
D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite.
Definition
ChEBI: A D-alpha-amino acid that is the D-isomer of arginine.
References
https://www.alfa.com/zh-cn/catalog/A16137/
Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993.
Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008).
Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.
D(-)-Arginine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ADVENT CHEMBIO PRIVATE LIMITED | +91-9821524116 +91-9821524116 | Mumbai, India | 353 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Santo Righello Pvt. Ltd | 91-9885571757 | Hyderabad, India | 919 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ADVENT CHEMBIO PRIVATE LIMITED | 58 |
| CHEMSWORTH | 30 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| Anand Agencies | 58 |
| Maas Pharma Chemicals | 58 |
| Santo Righello Pvt. Ltd | 58 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
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