Cyclopentadecanone
- CAS No.
- 502-72-7
- Chemical Name:
- Cyclopentadecanone
- Synonyms
- MUSK 15;exalton;EXALTONE;Normuscon;NORMUSCONE;CYCLOPENTADECONE;Cyclopentadecanon;CYCLOPENTADECANONE;CYCLOPENTANDECANONE;Exaltone~Normuscone
- CBNumber:
- CB2416348
- Molecular Formula:
- C15H28O
- Molecular Weight:
- 224.38
- MOL File:
- 502-72-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/27 18:15:55
| Melting point | 63-65 °C (lit.) |
|---|---|
| Boiling point | 120 °C/0.3 mmHg (lit.) |
| Density | 0.897 g/mL at 25 °C (lit.) |
| vapor pressure | 0.009Pa at 40℃ |
| refractive index | 1.4637 (estimate) |
| Flash point | 120°C/0.3mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Alcohol |
| form | powder to crystal |
| color | Colourless crystal needles. |
| Odor | at 10.00 % in dipropylene glycol. powdery musk animal natural greasy |
| Odor Type | musk |
| Water Solubility | 578μg/L at 20℃ |
| BRN | 1618444 |
| LogP | 5.6 at 20℃ |
| CAS DataBase Reference | 502-72-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Cyclopentadecanone(502-72-7) |
| EPA Substance Registry System | Cyclopentadecanone (502-72-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | GY0900000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29142900 | |||||||||
| NFPA 704 |
|
Cyclopentadecanone price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C111201 | Cyclopentadecanone 98% | 502-72-7 | 5G | ₹5141.88 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C1422 | Cyclopentadecanone min. 98.0 % | 502-72-7 | 5G | ₹2400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C1422 | Cyclopentadecanone min. 98.0 % | 502-72-7 | 25G | ₹8300 | 2022-05-26 | Buy |
Cyclopentadecanone Chemical Properties,Uses,Production
Chemical Properties
Cyclopentadecanone is a musk fragrance found in the
scent gland of the male civet cat.
A number of syntheses have been developed for its manufacture [260]. Among
these, the so-called Story procedure is the only route that has the potential to
make cyclopentadecanone available on a larger scale, but due to the handling of
hydroperoxides, the process is difficult to manage.
The process starts from tricyclohexylidene triperoxide, which is obtained by
oxidation of cyclohexanone with hydrogen peroxide. Pyrolysis leads to a mixture
of 1,16-hexadecanolide and cyclopentadecane. The latter is oxidized by oxygen
under boric acid catalysis to cyclopentadecanol, which is subsequently oxidized
to cyclopentadecanone.
Due to the availability of long-chained aliphatic dicarboxylic acids by biotechnological
processes, a Dieckmann condensation reaction may also possibly
be a useful route to produce this macrocyclic ketone.
Cyclopentadecanone is used in fine fragrances：
Occurrence
Reported to be found in the scent glands of the Louisiana muskrat Ondatra zibethicus rivalicius (Guenther, 1949).
Uses
Cyclopentadecanone is the main odoriferous component of musk.
Preparation
By the cyclization of dinitriles in high dilution (Bedoukian. 1967).
Metabolism
Ketones are not readily metabolized, although most of them probably undergo appreciable reduction to the corresponding secondary alcohols, which are excreted in the urine as glucuronic acid conjugates (Williams, 1959). Cyclopentadecanone was hydroxylated in cultures of four steroid-hydroxylating fungi (Calonectria decora, Rhizopus nigricans, Daedalea rufescens and Ophiobolus herpotrichus), but was not affected by Aspergillus ochraceus. Initial attack occurred at the most remote carbon atom, with yields of up to 26% of 8-hydroxycyclopentadecanone, plus dihydroxy compounds and more polar products (Ashton, Bailey & Jones, 1974).
Purification Methods
Subliming Exaltone is better than crystallising it from aqueous EtOH for purification. The semicarbazone has m 186-187o. [Stevens & Erickson J Am Chem Soc 64 146 1942, Mathur et al. J Chem Soc 3505 1963, Biens & Hess Helv Chim Acta 71 1704 1988, Beilstein 7 III 203, 7 IV 118.]
Cyclopentadecanone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7621 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8821 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
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