SPDP
![SPDP Structure](CAS/GIF/68181-17-9.gif)
- CAS No.
- 68181-17-9
- Chemical Name:
- SPDP
- Synonyms
- SPDP;SPDP NHS ester;SPDP Crosslinker;3-(2-PYRIDYLDITHIO)-PROPIONIC ACID-OSU;SUCCINIMIDYL 3-(2-PYRIDYLDITHIO)PROPIONATE;N-SUCCINIMIDYL 3-[2-PYRIDYLDITHIO]PROPIONATE;3-(Pyridin-2-yldisulfanyl)-propionic acid-OS;3-(PYRIDIN-2-YLDISULFANYL)-PROPIONIC ACID-OSU;N-SUCCINIMIDYL-3-(2-PYRIDYLDITHIO)PROPIONANATE;N-[3-(2-Pyridyldithio)propionyloxy]succinimide
- CBNumber:
- CB2446059
- Molecular Formula:
- C12H12N2O4S2
- Molecular Weight:
- 312.36
- MOL File:
- 68181-17-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/27 16:40:14
Melting point | 84-86 °C(lit.) |
---|---|
Boiling point | 465.9±55.0 °C(Predicted) |
Density | 1.48±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | acetone: 50 mg/mL |
form | powder |
pka | 1.76±0.19(Predicted) |
color | White to Light Yellow |
BRN | 1548137 |
Stability | Hygroscopic, Moisture Sensitive |
InChIKey | JWDFQMWEFLOOED-UHFFFAOYSA-N |
CAS DataBase Reference | 68181-17-9(CAS DataBase Reference) |
SPDP price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P3415 | 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester ≥95%, powder | 68181-17-9 | 5MG | ₹4297.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P3415 | 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester ≥95%, powder | 68181-17-9 | 25MG | ₹12676.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P3415 | 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester ≥95%, powder | 68181-17-9 | 100MG | ₹39554.55 | 2022-06-14 | Buy |
TCI Chemicals (India) | S0819 | N-Succinimidyl 3-(2-Pyridyldithio)propionate | 68181-17-9 | 100MG | ₹5500 | 2022-05-26 | Buy |
TCI Chemicals (India) | S0819 | N-Succinimidyl 3-(2-Pyridyldithio)propionate | 68181-17-9 | 250MG | ₹5800 | 2022-05-26 | Buy |
SPDP Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
It has been used for antibody conjugation and as a protein cross-linker.
General Description
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. It incorporates four atom linker.
SPDP Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
Supplier | Advantage |
---|---|
GLR Innovations | 58 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Triveni chemicals | 58 |
Clearsynth Labs | 58 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
career henan chemical co | 58 |
BOC Sciences | 58 |
Chongqing Chemdad Co., Ltd | 58 |
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