1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
- CAS No.
- 4004-05-1
- Chemical Name:
- 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
- Synonyms
- DOPE;1,2-Dioleoyl-sn-glycero-3-PE;(Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate;18:1 PE;PE(18:1(9Z)/18:1(9Z));COATSOME ME-8181 (DOPE);L-β,γ-Dioleoyl-α-cephalin;L-β,γ-Dioleoyl-α-Cephalin;18:1 (Delta9-Cis) PE (DOPE);Dioleoyl phosphoethanolamine
- CBNumber:
- CB2477530
- Molecular Formula:
- C41H78NO8P
- Molecular Weight:
- 744.05
- MOL File:
- 4004-05-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/20 11:41:24
| Melting point | 200°C(lit.) |
|---|---|
| Boiling point | 759.2±70.0 °C(Predicted) |
| Density | 1.008±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: 31.25 mg/mL (42.00 mM) |
| form | lyophilized powder |
| pka | 1.17±0.50(Predicted) |
| color | White to Light yellow |
| BRN | 1718431 |
| InChIKey | MWRBNPKJOOWZPW-XFBMKQTANA-N |
| SMILES | [C@H](COP(O)(=O)OCCN)(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC |&1:0,r| |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H319-H331-H336-H351-H361d-H372-H412 |
| Precautionary statements | P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-38-40-48/20/22-67-36/38-20-63 |
| Safety Statements | 36/37-26 |
| RIDADR | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| F | 8-10-23 |
| HS Code | 29232000 |
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P1223 | L-α-Phosphatidylethanolamine, dioleoyl ≥99% (GC), ≥98% (TLC), lyophilized powder | 4004-05-1 | 25MG | ₹14343.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P1223 | L-α-Phosphatidylethanolamine, dioleoyl ≥99% (GC), ≥98% (TLC), lyophilized powder | 4004-05-1 | 100MG | ₹29444 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P1223 | L-α-Phosphatidylethanolamine, dioleoyl ≥99% (GC), ≥98% (TLC), lyophilized powder | 4004-05-1 | 500MG | ₹88018.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 76548 | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine ≥97.0% (TLC) | 4004-05-1 | 100MG | ₹17200.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 76548 | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine ≥97.0% (TLC) | 4004-05-1 | 1G | ₹74486.83 | 2022-06-14 | Buy |
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine Chemical Properties,Uses,Production
Description
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar vesicles (GUVs).
Phosphatidylethanolamine (PE) is formed primarily in the reaction of CDP-ethanolamine and diacylglycerol. PE is one of the major components of cell membranes in bacteria and in nervous system.
Chemical Properties
Yellowish wax
Uses
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents.
Definition
ChEBI: Dioleoyl phosphatidylethanolamine is a phosphatidylethanolamine in which the phosphatidyl acyl groups are both oleoyl.
General Description
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (18:1 (Δ9-Cis) PE (DOPE)) is a neutral phospholipid and displays sensitivity towards pH change. At acidic it is an inverted hexagonal micelle and transforms to spherical micelle at alkaline pH.
Biological Activity
DOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy).
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 163)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | China | 176 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12832 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | China | 5857 | 58 | Inquiry |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | China | 18148 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 18750 | 58 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 8497 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32161 | 58 | Inquiry |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | China | 9311 | 58 | Inquiry |
Related Qustion
- Q:What is 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine?
- A:1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a metabolite of Escherichia coli with a structure containing 18:1 fatt....
- Mar 14，2024
4004-05-1(1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine)Related Search:
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
PHOSPHATIDYLETHANOLAMINE
PHOSPHATIDYLETHANOLAMINE
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamino caproylmaleimide
L-3-PHOSPHATIDYL[2-14C]ETHANOLAMINE,1,2-DIOLEOYL
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLETHANOLAMINE
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamino (+)-biotin
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
DOPS
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[3-(2-PYRIDYLDITHIO)PROPIONATE]
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DANSYL-LABELED
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(CARBOXYFLUORESCEIN)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(LISSAMINE RHODAMINE B SULFONYL)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, PYRENE-LABELED
chevron_left
1of4
chevron_right
3-SN-PHOSPHATIDYLETHANOLAMINE, 1,2-DIDEOYL
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
1,2-DI([CIS]-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
18:1 PE
L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL
L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL (C18:1,[CIS]-9)
L-BETA,GAMMA-DIOLEOYL-ALPHA-CEPHALIN
DIOLEOYL PHOSPHATIDYL ETHANOLAMINE
L-A-phosphatidylethanolamine dioleoyl
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-ETHA-N OLAMINE, 10 MG/ML
COATSOME ME-8181 (DOPE)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, >99%
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, DOPE
L-α-Phosphatidylethanolamine, dioleoyl
3-sn-Phosphatidylethanolamine, 1,2-dideoyl, L-β,γ-Dioleoyl-α-cephalin, DOPE
(+)-1-O,2-O-Dioleoyl-L-glycerol 3-(phosphoric acid 2-aminoethyl) ester
1,2-Dioleoyl-3-sn-phosphatidylethanolamine
O-(1-O,2-O-Dioleoyl-L-glycero-3-phospho)-2-aminoethanol
Phosphoric acid hydrogen (2-aminoethyl)[(2R)-2,3-bis(oleoyloxy)propyl] ester
Dioleoyl phosphoethanolamine
(9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine
L-β,γ-Dioleoyl-α-cephalin
PE(18:1(9Z)/18:1(9Z))
L-A-PHOSPHATIDYLETHANOLAMINE, DIOLEO
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine≥ 98% (HPTLC)
2-Aminoethyl (R)-2,3-bis(oleoyloxy)propyl hydrogen phosphate
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLETHANOLAMINE
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 98+%
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
9-Octadecenoic acid (9Z)-, 1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
18:1 (Delta9-Cis) PE (DOPE)
dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE)
9-Octadecenoic acid (9Z)-,(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediylester
DOPE
1,2-Dioleoyl-sn-glycero-3-PE
(Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate
L-β,γ-Dioleoyl-α-Cephalin
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamin
DOPE 1,2-dioloyl-sn-glycero-3-phosphoyl-ethanolamine
4004-05-1
4004/5/1
BioChemical
Biochemicals and Reagents
Glycerophosphonoethanolamines
Glycerides
Cloning and Expression
Lipids
Molecular Biology
Phosphoglycerides
Transfection & Transformation