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GW 766994

GW 766994 Structure
CAS No.
408303-43-5
Chemical Name:
GW 766994
Synonyms
GW 994;GW 766994;Benzamide, 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]-
CBNumber:
CB25419748
Molecular Formula:
C21H24Cl2N4O3
Molecular Weight:
451.35
MOL File:
408303-43-5.mol
Modify Date:
2024/7/2 8:55:04
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GW 766994 Properties

Boiling point 685.8±55.0 °C(Predicted)
Density 1.331±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:56.0(Max Conc. mg/mL);124.07(Max Conc. mM)
form A solid
pka 13.40±0.46(Predicted)
color Light yellow to yellow

GW 766994 Chemical Properties,Uses,Production

Description

GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 μM.

GW 766994 Preparation Products And Raw materials

Raw materials

2-MorpholineMethanaMine, 4-[(3,4-dichlorophenyl)Methyl]-, (2S)- 4-AMINOMETHYL-BENZAMIDE

Preparation Products

GW 766994 Suppliers

Global( 16)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4551 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 China 5012 58 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 China 11289 58 Inquiry
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 China 2380 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Nantong QuanYi Biotechnology Co., Ltd 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
MedChemExpress 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Kaifeng Mingren Pharmaceutical Co.,LTD 58
GW 766994 GW 994 Benzamide, 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]- 408303-43-5