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BRL 54443

BRL 54443 Structure
CAS No.
57477-39-1
Chemical Name:
BRL 54443
Synonyms
CS-1781;BRL 54443;BRL 54443 HCl;BRL 54443, >=98%;BRL-54443;BRL54443;BRL 54443 USP/EP/BP;BRL54443;BRL 54443;BRL-54443;3-(1-methylpiperidin-4-yl)-1H-indol-5-ol;3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol;1H-Indol-5-ol, 3-(1-Methyl-4-piperidinyl)-
CBNumber:
CB2690838
Molecular Formula:
C14H18N2O
Molecular Weight:
230.31
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00

BRL 54443 Properties

Boiling point 431.5±45.0 °C(Predicted)
Density 1.196
storage temp. Inert atmosphere,2-8°C
solubility H2O: 50 mg/mL
form solid
pka 10.08±0.40(Predicted)
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

BRL 54443 Chemical Properties,Uses,Production

Biological Activity

A potent 5-ht 1E/1F receptor agonist (pEC 50 values are 8.5 and 8.6 respectively). Displays > 30-fold selectivity over other 5-HT and dopamine receptors (pK i values are 8.7. 8.9, 7.2, 6.9, 7.2, 5.9, 7.0, 6.5, < 6, < 6, 6.3 and 6.2 for human 5-HT 1E , 1F , 1A , 1B , 1D , 2A , 2B , 2C , 4 , 7 , D 2 and D 3 receptors respectively). Induces 5-HT 2A receptor-mediated mouse aortic contraction in vitro (pEC 50 = 6.52). Active in vivo .

BRL 54443 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 141)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29900 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26165 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry

BRL 54443 Spectrum

BRL 54443 5-HYDROXY-3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOLE 3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol 3-(1-Methyl-4-piperidinyl)-1H-indol-5-ol BRL 54443 3-(1-methylpiperidin-4-yl)-1H-indol-5-ol 1H-Indol-5-ol, 3-(1-Methyl-4-piperidinyl)- BRL 54443 HCl BRL-54443;BRL54443 BRL 54443, >=98% BRL54443;BRL 54443;BRL-54443 CS-1781 BRL 54443 USP/EP/BP 57477-39-1 Inhibitors