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PHOLCODINE

PHOLCODINE Structure
CAS No.
509-67-1
Chemical Name:
PHOLCODINE
Synonyms
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol;Memine;pha-ol;Codylin;Ethnine;Galphol;pholtex;Dia-tuss;Folkodin;Hibernyl
CBNumber:
CB2704131
Molecular Formula:
C23H30N2O4
Molecular Weight:
398.5
MOL File:
509-67-1.mol
Modify Date:
2023/5/15 10:44:02
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PHOLCODINE Properties

Melting point 91°C
Boiling point 521.67°C (rough estimate)
Density 1.1772 (rough estimate)
refractive index 1.6300 (estimate)
solubility Sparingly soluble in water, freely soluble in acetone and in ethanol (96 per cent). It dissolves in dilute mineral acids.
form Solid
pka pKa 5.30(50% aq EtOH) (Uncertain)
color Light Brown

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Toxicity LD50 oral in mouse: 1gm/kg

PHOLCODINE Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

Antitussive; an opioid cough suppressant. Controlled Substance.

Definition

ChEBI: A morphinane alkaloid that is a derivative of morphine with a 2-morpholinoethyl group at the 3-position.

PHOLCODINE Preparation Products And Raw materials

Raw materials

Preparation Products

509-67-1(PHOLCODINE)Related Search:

PHOLCODINE ETHYLMORPHINE PHOLCODINE - REFERENCE SPECTRUM PHOLCODINE IMP. A (PHARMEUROPA) AS HEMISULPHATE PENTAHEMIHYDRATE: MORPHINE HEMISULPHATE PENTAHEMIHYDRATE[CONTROLLED SUBSTANCE PHOLCODINE IMP. B (PHARMEUROPA) AS PHOSPHATE HEMIHYDRATE: CODEINE PHOSPHATE HEMIHYDRATE[CONTROLLED SUBSTANCE]
Pholcodine - * narc PHOLCODINE IMP. A (PHARMEUROPA) AS HYDROCHLORIDE TRIHYDRATE: MORPHINE HYDROCHLORIDE TRIHYDRATE [CONTROLLED SUBSTANCE] CHEMBRDG-BB 9071306 o-bis(2,3-epoxypropoxy)benzene Pholcodine for peak identification - * narc
PHOLCODINE IMP. B (PHARMEUROPA) AS MONOHYDRATE: CODEINE MONOHYDRATE[CONTROLLED SUBSTANCE] PHOLCODINE-N-OXIDE 2-(3,4-DIMETHYL-PHENOXY)-ETHYLAMINE CHEMBRDG-BB 9071974 2-(2-ETHOXY-PHENOXY)-ETHYLAMINE
CHEMBRDG-BB 9071359 Piperidine, 2-[(4-ethoxyphenyl)methyl]- (9CI)
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3-(2-(4-Morpholinyl)ethyl)morphine 3-(2-Morpholinoethyl)morphine 3-Morpholylaethylmorphin 3-o-(2-morpholinoethyl)-morphin 7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-al 7,8-Didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-alpha-ol beta-Morpholinoethylmorphine beta-Morpholinylethylmorphine Codylin Dia-tuss Ethnine Ethnine Simplex Folcodine Folkodin Galenphol Galphol Glycodine Hibernyl Homocodeine Memine Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)- tussokon Weifacodine PHOLCODINE O3-(2-morpholinoethyl)morphine Pholcodine (PI) (5α,6α)-7,8-Didehydro-4,5-epoxy-17-Methyl-3-[2-(4-Morpholinyl)ethoxy]Morphinan-6-ol 3-O-(2-Morpholinoethyl)Morphine 7,8-Didehydro-4,5α-epoxy-17-Methyl-3-(2-Morpholinoethoxy)Morphinan-6α-ol Biocalyptol Folcodin Neocodine O-2-MorpholinoethylMorphine Pholcodine for peak identification morphinan-6-alpha-ol,7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoet Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5alpha,6alpha)- Morphine, 03-(2-morpholinoethyl)- Morphine, 3-O-(2-morpholinoethyl)- Morpholinylethylmorphine Neocodin o(sup3)-(2-morpholinoethyl)-morphin o(sup3)-(2-morpholinoethyl)morphine O3-(2-Morpholinoethyl)morphine Pectolin pha-ol Pholcodin pholtex Prodromine Tetrahydro-1,4-oxazinylmethylcodeine Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5α,6α)- (4R,4aR,7S,7aR,12bS)-3-methyl-9-(2-morpholin-4-ylethoxy)-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol 509-67-1 C23H30N2O4 C23H30N2O4H2O Heterocycles Intermediates & Fine Chemicals Pharmaceuticals