4-Hexylresorcinol
- CAS No.
- 136-77-6
- Chemical Name:
- 4-Hexylresorcinol
- Synonyms
- HEXYLRESORCINOL;4-HEXYLRESORCINOL;Hexylcaine;Oxana;ST-37;s.t.37;Adrover;Ascaryl;Hidesol;Prensol
- CBNumber:
- CB2725396
- Molecular Formula:
- C12H18O2
- Molecular Weight:
- 194.27
- MOL File:
- 136-77-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/11 19:21:31
| Melting point | 65-67 °C (lit.) |
|---|---|
| Boiling point | 333-335 °C (lit.) |
| Density | 1.0010 (rough estimate) |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index | 1.5050 (estimate) |
| Flash point | >100°C |
| storage temp. | 2-8°C |
| solubility | chloroform: 50 mg/mL, clear |
| pka | pKa 9.1 (Uncertain) |
| form | Powder and/or Chunks |
| color | White to pale orange or pale pink |
| PH | 7.7 (0.5g/l, H2O, 20℃) |
| Water Solubility | 0.05 g/100 mL (18 ºC) |
| Merck | 14,4712 |
| BRN | 2048312 |
| Stability | Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents. |
| InChIKey | WFJIVOKAWHGMBH-UHFFFAOYSA-N |
| LogP | 3.34 at 20℃ |
| Surface tension | 36.59mN/m at 1g/L and 20℃ |
| CAS DataBase Reference | 136-77-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Hexylresorcinol(136-77-6) |
| EPA Substance Registry System | 4-Hexylresorcinol (136-77-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H411 | |||||||||
| Precautionary statements | P264-P270-P273-P280-P301+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VH1575000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29072900 | |||||||||
| Toxicity | LD50 orally in Rabbit: 550 mg/kg | |||||||||
| NFPA 704 |
|
4-Hexylresorcinol price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.20647 | 4-Hexylresorcinol for synthesis | 136-77-6 | 25G | ₹5140 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 93513 | 4-Hexylresorcinol analytical standard | 136-77-6 | 25MG | ₹6549.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20647 | 4-Hexylresorcinol for synthesis | 136-77-6 | 100G | ₹16610 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 209465 | 4-Hexylresorcinol 98% | 136-77-6 | 25G | ₹3907.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 209465 | 4-Hexylresorcinol 98% | 136-77-6 | 100G | ₹14040.03 | 2022-06-14 | Buy |
4-Hexylresorcinol Chemical Properties,Uses,Production
Chemical Properties
slightly red powder
Preparation
The preparation of 4-Hexylresorcinol involves two methods:
The reaction of caproic acid and resorcinol in the presence of a catalyst.
Reduction of hexanoylresorcinol with zinc amalgam and dilute hydrochloric acid.
General Description
P-hexylresorcinol appears as pale-yellow viscous liquid (that becomes solid on standing at room temperature) or a peach colored powder. Pungent faintly fatty odor. Sharp astringent taste. (NTP, 1992)
Air & Water Reactions
Insoluble in water.
Reactivity Profile
4-Hexyl-1,3-benzenediol may be sensitive to prolonged exposure to light. Incompatible with acid chlorides, acid anhydrides and oxidizing agents .
Hazard
Irritant to respiratory tract and skin, concentrated solutions are vesicant.
Fire Hazard
Flash point data for 4-Hexyl-1,3-benzenediol are not available. 4-Hexyl-1,3-benzenediol is probably combustible.
Clinical Use
Hexylresorcinol, also known as 4-hexylresorcinol, is a white crystalline substance with a faint phenolic odor. When applied to the tongue it produces a sensation of numbness. It is freely soluble in alcohol but only slightly soluble in water(1–20,000 parts). Hexylresorcinol is an effective antiseptic,possessing both bactericidal and fungicidal properties.The phenol coefficient of hexylresorcinol against S. aureusis 98. As is typical for alkylated phenols, hexylresorcinol possesses surfactant properties. The compound also haslocal anesthetic activity. Hexylresorcinol is formulated into throat lozenges because of its local anesthetic and antisepticproperties. These preparations are probably of little value. Hexylresorcinol (in the concentration in thelozenge) is probably not antiseptic, and the local anestheticproperty can anesthetize the larynx, causing temporary laryngitis.
4-Hexylresorcinol Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| OPULENT PHARMA | +91-9106692785 +91-9106692785 | Gujarat, India | 479 | 58 | Inquiry |
| Chemicea Pharmaceuticals Pvt Ltd | +91-918482849343 +91-8482849343 | Mumbai, India | 461 | 58 | Inquiry |
| KROMOZOME | +91-91-9650900955 +91-09650900955 | Maharashtra, India | 71 | 58 | Inquiry |
| SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
| Vasant Chemicals Pvt Ltd | +919573466400 | Telangana, India | 18 | 58 | Inquiry |
| Salicylates and Chemicals Pvt. Ltd. | +91-8879630551 +91-8898005838 | Maharashtra, India | 61 | 58 | Inquiry |
| Prayag Pharmachem | +91-9921873418 +91-9921873418 | Maharashtra, India | 16 | 58 | Inquiry |
| Innovassynth Technologies (I) Ltd. | +91-2192260100 +91-7208872197 | Maharashtra, India | 118 | 58 | Inquiry |
| Mekong pharmaceuticals pvt ltd | +91-4035163894 +91-8008212221 | Telangana, India | 129 | 58 | Inquiry |
| Bhavi International Ltd | 91-22-25000429 | Maharashtra, India | 17 | 58 | Inquiry |
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