ZK 756326

CAS No.: 874911-96-3

Chemical Name:: ZK 756326

Synonyms: CS-2219;ZK 756326;ZK756326 2HCl;2-(2-(4-(3-Phenoxybenzyl)piperazin-1-yl)ethoxy)ethan-1-ol;2-[2-[4-[(3-Phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol;2-[2-[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-ethoxy]-ethanol;Ethanol, 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]-;2-(2-(4-(3-phenoxybenzyl)piperazin-1-yl)ethoxy)ethanoldihydrochloride;2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride

CBNumber:: CB2785596

Molecular Formula:: C21H28N2O3

Molecular Weight:: 356.46

MOL File:: 874911-96-3.mol

MSDS File:: SDS

Modify Date:: 2023/5/18 11:31:03

Request For Quotation

ZK 756326 Properties

storage temp.	Desiccate at RT
form	White solid.
Water Solubility	Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

ZK 756326 Chemical Properties,Uses,Production

Uses

2-?[2-?[4-?[(3-?Phenoxyphenyl)?methyl]?-?1-?piperazinyl]?ethoxy]?-ethanol is a nonpeptide CCR8 chemokine receptor agonist that inhibits the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM (1). It is a useful compound to investigate the physiological role of CCR8 in HIV infection.

Biological Activity

Selective, non-peptide CCR8 chemokine receptor agonist (IC 50 values are 1.8 and 2.6 μ M for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α 2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

ZK 756326 Preparation Products And Raw materials

Raw materials

Preparation Products

ZK 756326 Suppliers

Global( 50)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48467	58	Inquiry
Bide Pharmatech Ltd.	400-1647117 15221909166	China	63720	58	Inquiry
Henan Alpha Chemical Co., Ltd.	0371-55013243 15324716602	China	10015	58	Inquiry
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	China	2992	58	Inquiry
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	China	9708	58	Inquiry

Supplier	Advantage
CHEMSWORTH	30
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
Bide Pharmatech Ltd.	58
Henan Alpha Chemical Co., Ltd.	58
Suzhou Zhixin Biotechnology Co., Ltd.	58
Shanghai EFE Biological Technology Co., Ltd.	58

874911-96-3(ZK 756326)Related Search:

(+)-ZK 216348 ZK824859 ZK824859 ZK 158252 ZK164015

ZK756326(dihydrochloride) ZK 93426 hydrochloride ZK 159222 ZK118182 isopropyl ester ZK-90055 (hydrochloride)

ZK 110841 ZK 112993 FUDAEUIGIJZUAY-UMIRZPQISA-N ZK-261991 ZK 756326

1-[2(2-Hydroxyethoxy)ethyl]piperazine dihydrochloride

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ZK 756326 2-(2-(4-(3-phenoxybenzyl)piperazin-1-yl)ethoxy)ethanoldihydrochloride 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanoldihydrochloride 2-[2-[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-ethoxy]-ethanol ZK756326 2HCl CS-2219 2-[2-[4-[(3-Phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol Ethanol, 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]- 2-(2-(4-(3-Phenoxybenzyl)piperazin-1-yl)ethoxy)ethan-1-ol 874911-96-3 C21H28N2O32HCl