9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione

9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione Structure
CAS No.
68352-03-4
Chemical Name:
9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione
Synonyms
PubChem ID: 76962589;BYWOITQBHUGMQO-CHWIRLIISA-N;Fluocinolone Acetonide EP Impurity E;Fluocinolone Acetonide Impurity 5 (Fluocinolone Acetonide EP Impurity E);9,11β-Epoxy-6α-fluoro-21-hydroxy-16a,17-(1-methylethylidenedioxy)-9β-pregna-1,4-diene-3,20-dione;9β,11β-Epoxy-6α-fluoro-21-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione;9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione;9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione;(6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione;(6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-Methylethylidene)bis (oxy)]pregna-1,4-diene-3,20-dione
CBNumber:
CB2900085
Molecular Formula:
C24H29FO6
Molecular Weight:
432.48
MOL File:
68352-03-4.mol
Modify Date:
2023/5/4 15:15:38

9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione Properties

Melting point >202°C (dec.)
Boiling point 574.5±50.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly)
pka 12.85±0.10(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

SAFETY

Risk and Safety Statements

9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione Chemical Properties,Uses,Production

Uses

9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione can be used in the production of fluocinolone acetonide (F455800).

9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione Preparation Products And Raw materials

Raw materials

Preparation Products

9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione 9β,11β-Epoxy-6α-fluoro-21-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione (6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-Methylethylidene)bis (oxy)]pregna-1,4-diene-3,20-dione BYWOITQBHUGMQO-CHWIRLIISA-N Fluocinolone Acetonide EP Impurity E PubChem ID: 76962589 Pregna-1,4-diene-3,20-dione, 9,11-epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,9β,11β,16α)- Fluocinolone Acetonide Impurity 5 (Fluocinolone Acetonide EP Impurity E) (6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione 9,11β-Epoxy-6α-fluoro-21-hydroxy-16a,17-(1-methylethylidenedioxy)-9β-pregna-1,4-diene-3,20-dione 9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidene)dioxypregna-1,4-diene-3,20-dione 68352-03-4 Pharmaceuticals, Intermediates & Fine Chemicals, Steroids