ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Adrenal corticosteroids >Fluocinolone Acetonide
Fluocinolone Acetonide
- CAS No.
- 67-73-2
- Chemical Name:
- Fluocinolone Acetonide
- Synonyms
- synalar;Fluonid;dermalar;Fluocinolone acetonide for system suitability;6-alpha,9-alpha-difluoro-16-alpha-hydroxyprednisolone16,17-acetonide;jellin;synsac;Fluzon;localyn;synamol
- CBNumber:
- CB6394372
- Molecular Formula:
- C24H30F2O6
- Molecular Weight:
- 452.49
- MOL File:
- 67-73-2.mol
- Modify Date:
- 2024/11/16 15:32:52
| Melting point | 267-269 °C(lit.) |
|---|---|
| Boiling point | 578.5±50.0 °C(Predicted) |
| alpha | D +95° (chloroform) |
| Density | 1.1826 (estimate) |
| refractive index | 103 ° (C=1, MeOH) |
| storage temp. | Refrigerator |
| solubility | Practically insoluble in water, soluble in acetone and in ethanol |
| form | Solid |
| pka | 12.78±0.70(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble in water (partly), DMSO, alcohol, chloroform and methanol. |
| Merck | 14,4150 |
| InChIKey | FEBLZLNTKCEFIT-VSXGLTOVSA-N |
| CAS DataBase Reference | 67-73-2(CAS DataBase Reference) |
| EPA Substance Registry System | Fluocinolone acetonide (67-73-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-40-20/21/22 | |||||||||
| Safety Statements | 26-36-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TU3830000 | |||||||||
| HS Code | 2937220000 | |||||||||
| Toxicity | LD50 oral in rat: > 4gm/kg | |||||||||
| NFPA 704 |
|
Fluocinolone Acetonide price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | F8880 | Fluocinolone acetonide analytical standard | 67-73-2 | 100MG | ₹8486.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1397 | Fluocinolone Acetonide Pharmaceutical Secondary Standard; Certified Reference Material | 67-73-2 | 500MG | ₹10002.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | F8880 | Fluocinolone acetonide analytical standard | 67-73-2 | 1G | ₹52945.08 | 2022-06-14 | Buy |
Fluocinolone Acetonide Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Fluocinolone acetonide (Derma-Smoothe/FS, Flurosyn, Capex, Synalar) is a synthetic fluorinated corticosteroid.
Indications
Fluocinolone acetonide (Derma-Smoothe/FS, Flurosyn, Capex, Synalar) is a synthetic fluorinated corticosteroid.
Definition
ChEBI: A fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatme t of various skin disorders.
General Description
Fluocinolone acetonide,6α,9-difluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, also known as6α-fluorotriamcinolone acetonide, is the 21-acetate derivativeof fluocinolone acetonide and is about 5 times morepotent than fluocinolone acetonide in at least one topicalactivity assay.
Fluocinolone Acetonide Preparation Products And Raw materials
Raw materials
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Global( 482)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Coral Drugs Pvt Ltd | +91-1244518100 +91-8199986118 | New Delhi, India | 24 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Maharshi Pharma Chem | +91-7940359347 +91-7433927173 | Gujarat, India | 24 | 58 | Inquiry |
| Prachem Laboratories | +91-7948993109 +91-7383072020 | Gujarat, India | 44 | 58 | Inquiry |
| Dy - Mach Pharma | +91-2265018321 +91-2226833227 | Maharashtra, India | 18 | 58 | Inquiry |
| Swati Spentose Pvt Ltd | +91-2261505232 +91-2261505232 | Maharashtra, India | 44 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Horster Biotek Pvt Ltd | +91-7359657360 +91-9898127219 | Gujarat, India | 58 | 58 | Inquiry |
| Bhugan Lifescience Pvt Ltd | +91-9909430337 +91-8849461798 | Gujarat, India | 23 | 58 | Inquiry |
| Symbiotec Pharma Lab Pvt Ltd | +91-7316676406 +91-7316676405 | Madhya Pradesh, India | 71 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Coral Drugs Pvt Ltd | 58 |
| Gonane Pharma | 58 |
| Maharshi Pharma Chem | 58 |
| Prachem Laboratories | 58 |
| Dy - Mach Pharma | 58 |
| Swati Spentose Pvt Ltd | 58 |
| Ralington Pharma | 58 |
| Horster Biotek Pvt Ltd | 58 |
| Bhugan Lifescience Pvt Ltd | 58 |
| Symbiotec Pharma Lab Pvt Ltd | 58 |
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- Oct 8，2024
- Fluocinolone acetonide-Application
- Fluocinolone acetonide is a fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorin....
- Dec 12，2019
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(6-alpha,11-beta,16-alpha)-idene)bis(oxy))
(6alpha,11beta,16alpha)-idene)bis(oxy))
20-dione,6,9-difluoro-11,12-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-,(6-alpha,11-bpregna-4-diene-3
6alpha,9alpha-difluoro-16alpha-hydroxyprednisolone16,17-acetonide
fluocinolone16,17-acetonide
Fluocinoloneacetate
fluovitif
jellin
localyn
localynsyntex
percutina
pregna-1,4-diene-3,20-dione,6,9-difluoro-11,12-dihydroxy-16,17-((1-methylethyl
pregna-1,4-diene-3,20-dione,6,9-difluoro-11,21-dihydroxy-16,17-((1-methylethyl
pregna-1,4-diene-3,20-dione,6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydrox
radiocin
rs-1401at
synamol
synandrone
synsac
y-,cyclic16,17-acetalwithacetone
6α-Fluorotriamcinolone acetonide
Fluocinolone Acetonide (100 mg)
6α-Fluorotriamcinolone acetonide, Sinalar, Synandone, 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione, 6α,9α-Difluoro-16α-hydroxyprednisolone 16,17-acetonide
6a,9a-Difluoro-16a-hydroxyprednisolone 16,17-acetonide
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,12-dihydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-, (6.alpha.,11.beta., 16.alpha.)-
6α,9-Difluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
6α,9α-Difluoro-11β,21-dihydroxy-16α,17α-(isopropylidenebisoxy)pregna-1,4-diene-3,20-dione
6α,9α-Difluoro-16α-hydroxyprednisolone-16,17-acetonide
Fluocinonlone acetonide
(6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-Methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Fluocinolone Acetonide (anhydrous)
Fluocinolone Acetonide, 98.0%(LC)
Flucort-N
Fluocinolone acetonide Solution, 100ppm
Free Fuqing Song
Fuqing Song
Fluocinolone Acetonide (anhydrous) solution,1000ppm
Fluocinolone acetonide USP
Fluocinolone Acetonide (anhydrous) solution,100ppm
Fluocinoloe Acetonide
SYNANDONE
SINALAR
6a,9a-fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
6ALPHA-FLUOROTRIAMCINOLONE ACETONIDE
6ALPHA-9ALPHA-DIFLUORO-11BETA,16ALPHA,17ALPHA,21-TETRAHYDROXY-1,4-PREGNADIENE-3,20-DIONE
6ALPHA-9ALPHA-DIFLUORO-16ALPHA-HYDROXYPREDNISILONE 16,17-ACETONIDE
1,4-PREGNADIEN-6-ALPHA, 9-ALPHA-DIFLUORO-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE
Fluocinolone Acetonide BP/USP/EP
Fluocinonide CP2000
FluocinoloneAcetonideBp93
Mikronised
6α,9α-difluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
FLUOCINOLONEACETONIDE,ANHYDROUS,MICRONIZED,USP
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy- 16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11,16α)-
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-Acetonide
(6a,11,16a)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
6a-Fluorotriamcinolone Acetonide
Fluzon