enbucrilate
- CAS No.
- 6606-65-1
- Chemical Name:
- enbucrilate
- Synonyms
- n-Butyl Cyanoacrylate;Indermil;Tisuacryl;Integuseal;Hystoacryl;Glubranh 1;enbucrilate;Sicomet 6000;Histacryl Blue;InteguSeal Clear
- CBNumber:
- CB2929958
- Molecular Formula:
- C8H11NO2
- Molecular Weight:
- 153.18
- MOL File:
- 6606-65-1.mol
- Modify Date:
- 2024/7/10 10:35:40
| Boiling point | bp1.8 68° |
|---|---|
| Density | d20 0.989 |
| vapor pressure | 1.3hPa at 20℃ |
| refractive index | n20D 1.4424; nD25 1.4410 |
| Flash point | closed cup: >176°F (>80°C) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless |
| InChI | InChI=1S/C8H11NO2/c1-3-4-5-11-8(10)7(2)6-9/h2-5H2,1H3 |
| InChIKey | JJJFUHOGVZWXNQ-UHFFFAOYSA-N |
| SMILES | C(OCCCC)(=O)C(C#N)=C |
| LogP | 1.29 at 25℃ and pH7 |
| Surface tension | 34.28mN/m at 1g/L and 20℃ |
| EPA Substance Registry System | Butyl 2-cyanoacrylate (6606-65-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312+P330-P501 |
enbucrilate Chemical Properties,Uses,Production
Uses
Enbucrilate is bacteriostatic and its use is usually painless. It is used as an adhesive for lacerations of the skin, and in the treatment of bleeding from vascular structures.
Clinical Use
Enbucrilate injection of esophageal varices was first reported by Gotlib and Zimmermann in 1984 and has since been used in the acute treatment of bleeding esophageal varices in a few series, including randomized trials against band ligation for acute bleeding and for eradication of high-risk varices. Enbucrilate is often combined with lipiodol (lipid-soluble ethiodized oil) for injection of bleeding gastrointestinal ulcers; the advantage of this combination is slower polymerization of enbucrilate, with more accurate administration of the glue, but a potential disadvantage is a higher frequency of embolism, several cases of which have been reported. Overall, control of bleeding by using enbucrilate was found to be similar to band ligation, but rebleeding rates were higher. In addition, glue injection was found to be associated with sinus and fistula formation, in one case resulting in catastrophic bleeding. The higher complication rate may be explained by an increased risk of extravascular injection and attendant histotoxic reactions owing to the smaller lumen diameter.
enbucrilate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SG Pharma Pvt Ltd | +91-2227622000 +91-2227622000 | Maharashtra, India | 6 | 58 | Inquiry |
| Rusan Pharma Ltd | +91-2228687035 +91-9690022465 | Maharashtra, India | 14 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | China | 13096 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| SG Pharma Pvt Ltd | 58 |
| Rusan Pharma Ltd | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Henan Alfa Chemical Co., Ltd | 58 |
| Henan Fengda Chemical Co., Ltd | 58 |
| Capot Chemical Co.,Ltd. | 60 |
| Henan Tianfu Chemical Co.,Ltd. | 55 |
| BOC Sciences | 58 |
| Chongqing Chemdad Co., Ltd | 58 |
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