Osanetant

Osanetant Structure
CAS No.
160492-56-8
Chemical Name:
Osanetant
Synonyms
SR142801;SR-142801;Osanetant;Osanetant >=98% (HPLC);N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide;(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine;N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide;AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-;Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
CBNumber:
CB31179397
Molecular Formula:
C35H41Cl2N3O2
Molecular Weight:
606.62
MOL File:
160492-56-8.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:19

Osanetant Properties

Boiling point 727.9±60.0 °C(Predicted)
Density 1.25
storage temp. -20°C
solubility DMSO: soluble15mg/mL, clear
form powder
pka 8.33±0.10(Predicted)
color white to beige
optical activity [α]/D +18 to +24°, c = 1 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3

Osanetant price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0798 Osanetant ≥98% (HPLC) 160492-56-8 5MG ₹26034.13 2022-06-14 Buy
Sigma-Aldrich(India) SML0798 Osanetant ≥98% (HPLC) 160492-56-8 25MG ₹91601.15 2022-06-14 Buy
Product number Packaging Price Buy
SML0798 5MG ₹26034.13 Buy
SML0798 25MG ₹91601.15 Buy

Osanetant Chemical Properties,Uses,Production

Biochem/physiol Actions

Osanetant is a selective antagonist of neurokinin 3 receptor NK3. Neurokinins (tachykinins) are members of a family of at least three neuropeptides, substance P, neurokinin A, and neurokinin B (NKB), with each mediating their biological effects through binding to a preferred G-protein-coupled receptor termed NK1, NK2, or NK3, respectively. All three NK receptors are expressed in regions of the central nervous system that are related to emotion and cognition (i.e., amygdala and hippocampus) and have been linked to various degrees in psychiatric disorders. Neurokinin receptors, including NK3 receptors, are also expressed in the motor and sensory systems of the digestive tract. Osanetant was in clinical trials for both irritable bowel syndrome and schizophrenia.

Osanetant Preparation Products And Raw materials

Raw materials

Preparation Products

Osanetant Suppliers

Global( 16)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
DC Chemicals 021-58447131 13564518121 China 9412 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Axon Medchem BV +31-50-3118007 The Netherlands 477 30 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl- N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide (R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine SR142801 SR-142801 Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl- N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide Osanetant >=98% (HPLC) 160492-56-8 C35H41Cl2N3O2