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Thalicarpine

Thalicarpine Structure
CAS No.
5373-42-2
Chemical Name:
Thalicarpine
Synonyms
Nsc68075;Aids002681;Aids-002681;Thalicarpine;Thaliblastine;(6aS)-9-[4,5-Dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline;4H-Dibenzo[de,G]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6as)-;4H-Dibenzo(de,G)quinoline, 9-(4,5-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S-(R*,R*))-
CBNumber:
CB31179887
Molecular Formula:
C41H48N2O8
Molecular Weight:
696.83
MOL File:
5373-42-2.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:39
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Thalicarpine Properties

Melting point 160-161°
alpha D25 +133° (c = 0.83 in methanol); D25 +89° (c = 0.88 in chloroform)
Boiling point 701.43°C (rough estimate)
Density 1.1544 (rough estimate)
refractive index 1.4670 (estimate)
pka 7.62±0.40(Predicted)

Thalicarpine Chemical Properties,Uses,Production

Description

A complex alkaloid, thaliblastine occurs in Thalictrum minus elatum and has been assigned the structure given on the basis of chemical and spectroscopic investigations. The alkaloid has marked antitumour activity but rapid administration of the base causes brachycardia, hypotension and inhibition of respiration in laboratory animals. Slow intravenous injection, however, produces none of these effects. Thaliblastine is cytotoxic to HEF and Sa9 cells in vitro.

References

Todorov, Damyanova,Dokl. Bolg. Akad. Nauk., 28, 709 (1975)

Thalicarpine Preparation Products And Raw materials

Raw materials

Preparation Products

Thalicarpine Suppliers

Global( 3)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28091 58 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 55
TargetMol Chemicals Inc. 58
Lanospharma Laboratories Co.,Ltd 56

5373-42-2(Thalicarpine)Related Search:

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4-METHOXY-3'-METHYLBIPHENYL Thalicarpine 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-
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Thalicarpine (6aS)-9-[4,5-Dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Thaliblastine 4H-Dibenzo(de,G)quinoline, 9-(4,5-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S-(R*,R*))- 4H-Dibenzo[de,G]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6as)- Aids002681 Aids-002681 Nsc68075 5373-42-2 C41H48N2O8