Tiazofurine

Tiazofurine Structure
CAS No.
60084-10-8
Chemical Name:
Tiazofurine
Synonyms
TCAR;CI 909;Aids014479;tiazofurin;Riboxamide;NSC-286193;Aids-014479;NSC-286-193;Tiazofurine;Tiazofurinum
CBNumber:
CB31179908
Molecular Formula:
C9H12N2O5S
Molecular Weight:
260.269
MOL File:
60084-10-8.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:19

Tiazofurine Properties

Melting point 145-146°
alpha D25 -9° (c = 0.5 in ethanol)
Density 1.4797 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form Solid
color White to Pale Beige
Stability Very Very Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Tiazofurine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Definition

ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase).

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NSC-286193 NSC-286-193 Riboxamide TCAR 2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide Tiazofurine tiazofurin Aids014479 Aids-014479 2-β-D-Ribofuranosyl-4-thiazolecarboxaMide 2-β-D-Ribofuranosylthiazole-4-carboxaMide CI 909 2-b-D-Ribofuranosyl-4-thiazolecarboxaMide 4-Thiazolecarboxamide, 2-β-D-ribofuranosyl- 2-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide 2-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)thiazole-4-carboxamide Nucleoside Antimetabolite/Analog,NSC-286193,Inhibitor,Tiazofurin,inhibit,NSC286193,Orthopoxvirus Tiazofurinum 60084-10-8 Carbohydrates & Derivatives Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds