5-Aziridino-2,4-dinitrobenzamide
- CAS No.
- 21919-05-1
- Chemical Name:
- 5-Aziridino-2,4-dinitrobenzamide
- Synonyms
- CB-954;CB-1954;tretazicar;NSC 115829;CB 1954;CB-1954;Tretazicar (>Tretazicar (>94%);CB1954(TRETAZICAR);Tretazicar (CB 1954);5-Aziridino-2,4-dinitrobenzamide
- CBNumber:
- CB31216241
- Molecular Formula:
- C9H8N4O5
- Molecular Weight:
- 252.18
- MOL File:
- 21919-05-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:34
| Melting point | 173 °C |
|---|---|
| Boiling point | 427.2±45.0 °C(Predicted) |
| Density | 1.671±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 14.23±0.50(Predicted) |
| form | solid |
| color | Yellow to Dark Yellow |
| InChIKey | WOCXQMCIOTUMJV-UHFFFAOYSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 2933.99.7500 |
5-Aziridino-2,4-dinitrobenzamide price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C2235 | CB 1954 solid | 21919-05-1 | 50MG | ₹38601.95 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C3656 | CB-1954 | 21919-05-1 | 10MG | ₹4400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C3656 | CB-1954 | 21919-05-1 | 50MG | ₹14800 | 2022-05-26 | Buy |
5-Aziridino-2,4-dinitrobenzamide Chemical Properties,Uses,Production
Description
CB-1954 is a prodrug that is enzymatically activated to generate an antitumor agent that forms DNA-DNA interstrand crosslinks. In rat Walker 256 carcinoma cells, CB-1954 is reduced by NAD(P)H:quinone oxidoreductase (NQO1) to the cytotoxic derivative 5-(aziridin-1-yl)-4-hydroxylamineo 2 nitrobenzamide, a bifunctional alkylating agent.
Uses
5-Aziridino-2,4-dinitrobenzamide is an anticancer prodrug used in gene therapy research and is known to be activated by NAD(P)H Quinone Oxidoreductase 2.
Biochem/physiol Actions
CB 1954 is an anticancer prodrug used in gene therapy research; activated by NAD(P)H quinone oxidoreductase?2.
5-Aziridino-2,4-dinitrobenzamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 88)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| BOC Sciences | 58 |
| CONIER CHEM AND PHARMA LIMITED | 58 |
| Career Henan Chemica Co | 58 |
| InvivoChem | 58 |
| LEAP CHEM CO., LTD. | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | 58 |
21919-05-1(5-Aziridino-2,4-dinitrobenzamide)Related Search:
5-(1-aziridinyl)-2,4-dinitrobenzamide
NSC 115829
tretazicar
5-(1-Aziridinyl)-2,4-dinitrobenzamide, 5-(Aziridin-1-yl)-2,4-dinitrobenzamide
5-Aziridino-2,4-dinitrobenzamide
2,4-Dinitro-5-(aziridine-1-yl)benzamide
CB-954
CB-1954
5-(Aziridin-1-yl)-2,4-dinitrobenzamide
Benzamide, 5-(1-aziridinyl)-2,4-dinitro-
2,4-Dinitro-5-ethyleneiminobenzamide
Tretazicar (>94%)
Tretazicar (CB 1954)
CB 1954;CB-1954
CB1954(TRETAZICAR)
Tretazicar (>
Tretazicar,NQO1,DNA Alkylator/Crosslinker,rat,bifunctional,Inhibitor,inhibit,agent,cross-link,256,line,4-hydroxylamine,Walker,CB 1954,DNA,CB-1954,tumour
21919-05-1