Fluorochloridone
- CAS No.
- 61213-25-0
- Chemical Name:
- Fluorochloridone
- Synonyms
- RACER;r40244;raiser;4-CLTA;Racer 25;（3RS，4RS;Clostene;（3RS， 4RS;FLUROCHLORIDON;FLUORCHLORIDONE
- CBNumber:
- CB3125940
- Molecular Formula:
- C12H10Cl2F3NO
- Molecular Weight:
- 312.12
- MOL File:
- 61213-25-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/19 15:36:20
| Melting point | 67.65°C |
|---|---|
| Boiling point | 212.5 °C |
| Density | 1.3924 (estimate) |
| Flash point | >100 °C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -3.59±0.60(Predicted) |
| color | Pale Brown to Light Brown |
| LogP | 3.360 |
| CAS DataBase Reference | 61213-25-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyrrolidinone, 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-(61213-25-0) |
| EPA Substance Registry System | Flurochloridone (61213-25-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS08,GHS07,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H317-H360FD-H410 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P273-P391-P501 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-27-36/37/39 |
| RTECS | UY5746500 |
Fluorochloridone Chemical Properties,Uses,Production
Chemical Properties
Brown solid. Easily soluble in acetone, chlorobenzene, ethanol, xylene and other organic solvents, with a solubility of 100-150g/L. Solubility in kerosene <5g/L. The solubility in water is 28mg/L. Partition coefficient (n-octanol/water) 2300 (20°C). The half-life is 7d at 60°C and pH 4, 18d at 60°C and pH 7, and the half-life in soil is 11-100d.
Uses
Flurochloridone (FLC) is a monophenyl pyrrolidinone selective herbicide that can be used in herbicidal composition to control weed in crop fields. It is commonly used to inhibit weeds that occur during the growth of crop plants, such as grains, sunflowers, and potatoes.
Definition
ChEBI: Flurochloridone is a member of pyrrolidines, a member of (trifluoromethyl)benzenes and an organochlorine compound. It has a role as a carotenoid biosynthesis inhibitor, an agrochemical and a herbicide.
Metabolic pathway
From hydrolytic and photolytic studies of flurochloridone in buffer solution, no hydrolysis of flurochloridone occurs at pH 5, 7, or 9 at 25°C or at pH 5 at 40°C. Appreciable hydrolysis occurs at 40°C at pH 7 and 9 with half-lives of 190 and 140 days, respectively. Five hydrolytic degradation products and six photolytic degradation products are identified. The major photolytic degradation product which contains 39% of the radioactivity is 4-(chloromethyl)-3-hydroxy-1-[3- (trifluoromethyl)phenyl]-2-pyrrolidinone with a mixture of cis and trans isomers. The formation of this major degradation product suggests that the major photolytic pathway involves homolytic cleavage of the carbon ? chlorine bond at the 3-position of the pyrrolidinone ring and the free radical intermediate can react with water to give the major product or eliminate the hydrogen radical to form 4- (chloromethyl)-1,5-dihydro-1-[3- (trifluoromethyl)phenyl]pyrrol-2H-one.
Mode of action
Flurochloridone is the active substance of some pre-emergence herbicides. It has an inhibitory effect on the synthesis of carotenoids, which protect chlorophylls against oxidative stress.
Toxicity evaluation
The acute oral LD50 of male rats is 4000 mg/kg, the acute transdermal LD50 of rabbits is >5000 mg/kg, and the acute inhalation of rats is LC50 10.3 mg/L (4h). Slightly irritating to rabbit skin and eyes.
Fluorochloridone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12460 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20314 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21671 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8826 | 58 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |