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crebanine

crebanine Structure
CAS No.
25127-29-1
Chemical Name:
crebanine
Synonyms
Crebanin;crebanine;5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-9,10-dimethoxy-7-methyl-, (7R)-;(R)-9,10-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline
CBNumber:
CB31354172
Molecular Formula:
C20H21NO4
Molecular Weight:
339.39
MOL File:
25127-29-1.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:05

crebanine Properties

Melting point 126 °C
Boiling point 488.2±45.0 °C(Predicted)
Density 1.266±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Cryst.
pka 6?+-.0.20(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Toxicity mouse,LD50,intraperitoneal,24230ug/kg (24.23mg/kg),BEHAVIORAL: IRRITABILITYBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION,Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 20, Pg. 422, 1989.

crebanine Chemical Properties,Uses,Production

Uses

Crebanine is an aporphine alkaloid which helps sensitize TNF-α induced apoptosis and suppress human lung adenocarcinoma. Known to exhibit anticancer properties.

crebanine Preparation Products And Raw materials

Raw materials

Preparation Products

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crebanine Crebanin 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-9,10-dimethoxy-7-methyl-, (7R)- (R)-9,10-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline 25127-29-1