(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

CAS No.: 767340-03-4

Chemical Name:: (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

Synonyms: 7(8H)-;Sitagliptin-12;Sitagliptin Impurity 9;Sitagliptin Enamine Imp;3-a]pyrazine-7(8H)-yl]-1-(2;(Z)-3-amino-1-(3-(trifluoromethyl);5-trifluorophenyl)but-2-en-2-amine;(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5;(2Z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a];(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo-[4,3-a]pyrazine-7(8H)-yl]-1-(2,4

CBNumber:: CB31564663

Molecular Formula:: C16H13F6N5O

Molecular Weight:: 405.3

MOL File:: 767340-03-4.mol

MSDS File:: SDS

Modify Date:: 2023/4/23 13:52:06

Request For Quotation

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Properties

Melting point	178-180°C
Boiling point	555.1±60.0 °C(Predicted)
Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	4.11±0.70(Predicted)
color	White
CAS DataBase Reference	767340-03-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension.

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Suppliers

Global( 148)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.R. LIFE SCIENCES PVT. LTD.	+91-914040267679 +91-8519993257	Hyderabad, India	100	58	Inquiry
SynThink RESEARCH CHEMICALS	+91-8177860948 +91-8177860948	Mumbai, India	494	58	Inquiry
GLP Pharma Standards	+91 9866074638	Hyderabad, India	1644	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
Orgamine Chemicals(I) Pvt Ltd	+91-9820080281 +91-9820080281	Maharashtra, India	451	58	Inquiry
Aspen Biopharma Labs Pvt Ltd	+91-9248058660 +91-9248058662	Telangana, India	234	58	Inquiry
Actis Generics Pvt Ltd	+91-9949094333 +91-9866922779	AndhraPradesh, India	44	58	Inquiry
Molsyns Research	+91-9586858886 +91-9586858886	Gujarat, India	418	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry

Supplier	Advantage
A.R. LIFE SCIENCES PVT. LTD.	58
SynThink RESEARCH CHEMICALS	58
GLP Pharma Standards	58
Ralington Pharma	58
Orgamine Chemicals(I) Pvt Ltd	58
Aspen Biopharma Labs Pvt Ltd	58
Actis Generics Pvt Ltd	58
Molsyns Research	58
A.J Chemicals	58
CHEMSWORTH	30

767340-03-4((2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine)Related Search:

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one Terazosin hydrochloride Terazosin Dihydromyrcenol Alfuzosin hydrochloride

Glycine ALTRENOGEST Doxazosin mesylate Alfuzosin Prazosin

Doxazosin Pyrazine Sitagliptin Defuoro IMpurity 3 (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid Sitagliptin enaMine aMide iMpurity

Sitagliptin diaMide iMpurity BLDAVCZELRQXFP-OWOJBTEDSA-N Sitagliptin Impurity 21

chevron_left

1of4

chevron_right

(2Z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a] (2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine （2Z）-2-amine -4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro][1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl] -1-(2,4,5-trifluorophenyl)but-2-en (2-4) (2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-α]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 3-AMino-1-(3-trifluoroMethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluoro-phenyl)-but-2-en-1-one (2Z)-3-aMino-1-[3-(trifluoroMethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Z)-3-aMino-1-(3-(trifluoroMethyl) -5,6-dihydro-[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo-[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-t 7(8H)- 2-Buten-1-one, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)- (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo-[4,3-a]pyrazine-7(8H)-yl]-1-(2,4 (Z)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trif (Z)-3-amino-1-(3-(trifluoromethyl) Sitagliptin impurity 12/Sitagliptin Enamine Impurity/(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Sitagliptin-12 (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5 3-a]pyrazine-7(8H)-yl]-1-(2 5-trifluorophenyl)but-2-en-2-amine 3-Amino-1-(3-Trifluoromethyl)-5,6-Dihydro-8H-[1,2,4]Triazolo[4,3-A]Pyrazine-7-Yl-4-(2,4,5-Trifluorophenyl)But-2-En-2-Amine Sitagliptin Impurity 9 3-(1-Phenyl-ethylamino)-1-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin- 7-yl)-4-(2,4,5,trifluoro-phenyl)-butan-1-one Sitagliptin Enamine ImpurityQ: What is Sitagliptin Enamine Impurity Q: What is the CAS Number of Sitagliptin Enamine Impurity Q: What is the storage condition of Sitagliptin Enamine Impurity Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine Sitagliptin Enamine Imp (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine (Sitagliptin Impurity) 767340-03-4 C16H13F6N5O Pyrazine All Inhibitors Heterocycles Inhibitors Intermediates Intermediates & Fine Chemicals Pharmaceuticals