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Doxazosin

CAS No.: 74191-85-8

Chemical Name:: Doxazosin

Synonyms: UK 33274;UK 33,274;DOXAZOSIN;Doxazosin base;DOXAZOSINMESYTL;DOXAZOSIN(CARDULAR);Doxazosin USP/EP/BP;Doxazosin (UK 33274);Doxazosin Mesylate USP;DOXAZOSIN(SUBJECTTOPATENTFREE)

CBNumber:: CB7216507

Molecular Formula:: C23H25N5O5

Molecular Weight:: 451.48

MOL File:: 74191-85-8.mol

MSDS File:: SDS

Modify Date:: 2024/8/7 19:09:42

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Doxazosin Properties

Melting point	289-290°C
Boiling point	718.0±70.0 °C(Predicted)
Density	1.371±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Powder
pka	6.52±0.50(Predicted)
CAS DataBase Reference	74191-85-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05,GHS07,GHS08,GHS09
Signal word	Danger
Hazard statements	H302-H373-H411-H314
Precautionary statements	P260-P264-P270-P273-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P391-P405-P501

Doxazosin Chemical Properties,Uses,Production

Description

Doxazosin mesylate is a selective alpha, blocker indicated for the treatment of hypertension, reportedly of special benefit as a first-line agent in the most hypertonic patient population. Another advantage of doxazosin is its favorable effect on blood lipids; it significantly increases the HDL/total cholesterol ratio and decreases the total cholesterol as well as triglycerides levels.

Uses

ACIPHEX therapeutic Erosive or Ulcerative Gastroesophageal Reflux Disease

Definition

ChEBI: A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl roup at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

General Description

Doxazosin, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazine(Cardura), is a quinazoline compound that selectively inhibitsthe α1-subtype of α-adrenergic receptors. This agentis very useful in the management of hypertension associatedwith pheochromocytoma.

Doxazosin Preparation Products And Raw materials

Raw materials

2-(5-methyl-2-propan-2-yl-phenoxy)ethanamine 2-(1-Piperazinyl)pyrimidine ETHYLENE OXIDE Quinazoline

Preparation Products

Doxazosin Suppliers

Global( 127)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
AARTIA KEM SCIENCE	+91-8291072530 +91-8291072530	Maharashtra, India	70	58	Inquiry
AKASH PHARMA EXPORTS	+91-9388123451 +91-9846039283	Kerela, India	470	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Thykn India International	08048372611Ext 128	Mumbai, India	22	58	Inquiry
Medicea Impex Private Limited	07942544983	Nagpur, India	24	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	China	5867	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29888	58	Inquiry

Supplier	Advantage
AARTIA KEM SCIENCE	58
AKASH PHARMA EXPORTS	58
CLEARSYNTH LABS LTD.	58
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Thykn India International	58
Medicea Impex Private Limited	58
Pharma Affiliates	58
Hebei Chuanghai Biotechnology Co,.LTD	58
career henan chemical co	58

Doxazosin Spectrum

Doxazosin(74191-85-8)¹HNMR

74191-85-8(Doxazosin)Related Search:

Prazosin Prazosin hydrochloride Tamsulosin Doxazosin mesylate Terazosin

Azoazine intermediate Quinazoline Benzene 1,4-Benzodioxan DOXAZOSIN-D8 (PIPERAZINE-D8)

6'-HYDROXY DOXAZOSIN DOXAZOSIN MALEATE Doxazosin

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[4-(4-amino-6,7-dimethoxy-quinazolin-2- yl)piperazin-1-yl]-(2,5-dioxabi cyclo[4.4.0]deca-6,8,10-trien-4-yl)methanone DOXAZOSIN DoxazosinMesylate77883-43-3/Base DOXAZOSIN(SUBJECTTOPATENTFREE) Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]- UK 33,274 UK 33274 4-Amino-2-[4-(1，4-benzodioxan-2-carbonyl)piperazin-1-y1]-6，7-dimethoxy quinazoline 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine 1-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine 6,7-Dimethoxy-2-[4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-1-piperazinyl]quinazoline-4-amine DOXAZOSINMESYTL 1-(4-aMino-6,7-diMethoxy-quinazolin-2-yl)-4-(2,3-dihydro-benzo[1,4]dioxine-2-carbonyl)-piperazine DOXAZOSIN(CARDULAR) (4-(4-aMino-6,7-diMethoxyquinazolin-2-yl)piperazin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)Methanone Doxazosin Mesylate USP Methanone,[4-(4-aMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)- [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methanone Doxazosin USP/EP/BP Doxazosin base Doxazosin (UK 33274) DoxazosinQ: What is Doxazosin Q: What is the CAS Number of Doxazosin Q: What is the storage condition of Doxazosin COc5cc4nc(N3CCN(C(=O)C2COc1ccccc1O2)CC3)nc(N)c4cc5OC 74191-85-8 74191-85-5 C23H25N5O5 API API, Trade Name: Cardura & Carduran Doxazosin Pharmaceutical