Doxazosin
![Doxazosin Structure](CAS/GIF/74191-85-8.gif)
- CAS No.
- 74191-85-8
- Chemical Name:
- Doxazosin
- Synonyms
- UK 33274;UK 33,274;DOXAZOSIN;Doxazosin base;DOXAZOSINMESYTL;DOXAZOSIN(CARDULAR);Doxazosin USP/EP/BP;Doxazosin (UK 33274);Doxazosin Mesylate USP;DOXAZOSIN(SUBJECTTOPATENTFREE)
- CBNumber:
- CB7216507
- Molecular Formula:
- C23H25N5O5
- Molecular Weight:
- 451.48
- MOL File:
- 74191-85-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/7 19:09:42
Melting point | 289-290°C |
---|---|
Boiling point | 718.0±70.0 °C(Predicted) |
Density | 1.371±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | Powder |
pka | 6.52±0.50(Predicted) |
CAS DataBase Reference | 74191-85-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() ![]() GHS05,GHS07,GHS08,GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H302-H373-H411-H314 |
Precautionary statements | P260-P264-P270-P273-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P391-P405-P501 |
Doxazosin Chemical Properties,Uses,Production
Description
Doxazosin mesylate is a selective alpha, blocker indicated for the treatment of hypertension, reportedly of special benefit as a first-line agent in the most hypertonic patient population. Another advantage of doxazosin is its favorable effect on blood lipids; it significantly increases the HDL/total cholesterol ratio and decreases the total cholesterol as well as triglycerides levels.
Uses
ACIPHEX therapeutic Erosive or Ulcerative Gastroesophageal Reflux Disease
Definition
ChEBI: A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl roup at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
General Description
Doxazosin, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazine(Cardura), is a quinazoline compound that selectively inhibitsthe α1-subtype of α-adrenergic receptors. This agentis very useful in the management of hypertension associatedwith pheochromocytoma.
Doxazosin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
AARTIA KEM SCIENCE | +91-8291072530 +91-8291072530 | Maharashtra, India | 70 | 58 | Inquiry |
AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Thykn India International | 08048372611Ext 128 | Mumbai, India | 22 | 58 | Inquiry |
Medicea Impex Private Limited | 07942544983 | Nagpur, India | 24 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | China | 5867 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |