Alfuzosin hydrochloride
![Alfuzosin hydrochloride Structure](CAS/GIF/81403-68-1.gif)
- CAS No.
- 81403-68-1
- Chemical Name:
- Alfuzosin hydrochloride
- Synonyms
- URION;XATRAL;Alfoten;MITTOVAL;Uroxatral;UROXANTRAL;Udon:xatral;SL-77,499-10;ALFUZOSIN HCL;Alfuzosin-d7 HCl
- CBNumber:
- CB8703590
- Molecular Formula:
- C19H28ClN5O4
- Molecular Weight:
- 425.91
- MOL File:
- 81403-68-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/26 14:09:12
Melting point | 225°C |
---|---|
storage temp. | 2-8°C |
solubility | DMSO: >10mg/mL |
pka | 8.13(at 25℃) |
form | solid |
color | White to Off-White |
Merck | 14,238 |
CAS DataBase Reference | 81403-68-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | LT9965475 | |||||||||
HS Code | 2934990002 | |||||||||
NFPA 704 |
|
Alfuzosin hydrochloride price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1638 | Alfuzosin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 81403-68-1 | 1G | ₹9103.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A0232 | Alfuzosin hydrochloride ≥98% (HPLC), solid | 81403-68-1 | 5MG | ₹12308.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A0232 | Alfuzosin hydrochloride ≥98% (HPLC), solid | 81403-68-1 | 25MG | ₹49199.63 | 2022-06-14 | Buy |
TCI Chemicals (India) | A2591 | Alfuzosin Hydrochloride | 81403-68-1 | 100MG | ₹2300 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2591 | Alfuzosin Hydrochloride | 81403-68-1 | 1G | ₹8100 | 2022-05-26 | Buy |
Alfuzosin hydrochloride Chemical Properties,Uses,Production
Description
Alfuzosin (SL-77499) (I), a quinazoline derivative which is a uroselective alpha-1 adrenoreceptor antagonist, has been developed and launched worldwide by Sanofi-Synthelabo, for the treatment of benign prostate hyperplasia (BPH). In November 2003, alfuzosin (I) was launched as an extended release formulation in the US as Uroxatral utilizing Skyepharma’s oral controlled release technology.
Chemical Properties
White to Off-White Solid
Uses
α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Alfuzosin hydrochloride is used in treatment of benign prostatic hypertrophy.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biological Activity
Functionally uro-selective α 1 adrenoceptor antagonist that does not discriminate between α 1 subtypes. Inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Also relaxes corpus cavernosum tissue (pIC 50 = 7.64) in vitro .
Alfuzosin hydrochloride Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ALMELO PRIVATE LIMITED | +91-9100991345 +91-8500807769 | Telangana, India | 114 | 58 | Inquiry |
ANWITA APIS | +919000311012 | Hyderabad, India | 198 | 58 | Inquiry |
KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
Unichem Laboratories Ltd | +91-2266888333 +91-2266888333 | Maharashtra, India | 62 | 58 | Inquiry |
HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
Apotex Pharmachem India Pvt Ltd | +91-8022891034 +91-8022891000 | Karnataka, India | 109 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Supplier | Advantage |
---|---|
ALMELO PRIVATE LIMITED | 58 |
ANWITA APIS | 58 |
KARPSCHEM LABORATORIES | 58 |
Hetero Drugs Limited | 58 |
Unichem Laboratories Ltd | 58 |
HRV Global Life Sciences | 58 |
Aurobindo Pharma Limited | 58 |
Apotex Pharmachem India Pvt Ltd | 58 |
Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
Ralington Pharma | 58 |
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