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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Alfuzosin hydrochloride

Alfuzosin hydrochloride

Alfuzosin hydrochloride Structure
  • ₹2300 - ₹49199.63
  • Product name: Alfuzosin hydrochloride
  • CAS: 81403-68-1
  • MF: C19H28ClN5O4
  • MW: 425.91
  • EINECS:620-512-3
  • MDL Number:MFCD00879135
  • Synonyms:Alfuzosin-d7 HCl;Alfuzosin hydrochlorid;Alfuzosin Hydrochloride (150 mg);Alfuzosin hydrochloride(Uroxatral);Uroxatral;Alfuzosin hydrocholoride;Uroxatral hydrochloride;N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)-propyl)tetrahydrofuran-2-carboxamid
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2591
  • Product descriptionAlfuzosin Hydrochloride
  • Packaging100MG
  • Price₹2300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2591
  • Product descriptionAlfuzosin Hydrochloride
  • Packaging1G
  • Price₹8100
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA0232
  • Product descriptionAlfuzosin hydrochloride ≥98% (HPLC), solid
  • Packaging25MG
  • Price₹49199.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA0232
  • Product descriptionAlfuzosin hydrochloride ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹12308.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1638
  • Product descriptionAlfuzosin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9103.83
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2591 Alfuzosin Hydrochloride 100MG ₹2300 2022-05-26 Buy
TCI Chemicals (India) A2591 Alfuzosin Hydrochloride 1G ₹8100 2022-05-26 Buy
Sigma-Aldrich(India) A0232 Alfuzosin hydrochloride ≥98% (HPLC), solid 25MG ₹49199.63 2022-06-14 Buy
Sigma-Aldrich(India) A0232 Alfuzosin hydrochloride ≥98% (HPLC), solid 5MG ₹12308.03 2022-06-14 Buy
Sigma-Aldrich(India) PHR1638 Alfuzosin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9103.83 2022-06-14 Buy

Properties

Melting point :225°C
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :8.13(at 25℃)
form :solid
color :White to Off-White
Merck :14,238
CAS DataBase Reference :81403-68-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Alfuzosin is a post-synaptic α1-adrenergic receptor antagonist commonly used to improve lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It displays high-affinity with non-selectivity for the three known human α1 adrenoceptors (pKi = 8.0, 8.0, and 8.5 for α1A, α1B, and α1D, respectively). Consistent with a role for α1 adrenoceptors in mediating contraction of smooth muscle, alfuzosin was first described as having anti-hypertensive effects with peripheral vasodilator properties. In patients with BPH, alfuzosin increases mean urinary flow rate and decreases residual volume. Alfuzosin produces minimal vasodilatory and sexual function side effects.

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