3-Aminopropionitrile
- CAS No.
- 151-18-8
- Chemical Name:
- 3-Aminopropionitrile
- Synonyms
- 3-AMINOPROPANENITRILE;BAPN;β-aminopropionitrile;beta-Aminopropionitrile;AMINOPROPIONITRILE;2-CYANOETHYLAMINE;beta-Alaninenitrile;B-AMINOPROPIONITRILE;BETA-AMINOPROPIONONITRILE;e (stabiL
- CBNumber:
- CB3853135
- Molecular Formula:
- C3H6N2
- Molecular Weight:
- 70.09
- MOL File:
- 151-18-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/24 19:19:26
| Melting point | <25 °C |
|---|---|
| Boiling point | 185 °C |
| Density | 0.9584 |
| refractive index | 1.4365-1.4395 |
| Flash point | 79-81°C/16mm |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Chloroform, Methanol |
| form | Liquid |
| pka | 7.80(at 20℃) |
| color | Clear colorless to yellow |
| Water Solubility | Soluble in water. |
| Sensitive | Air & Moisture Sensitive |
| Merck | 14,469 |
| BRN | 1698848 |
| InChIKey | AGSPXMVUFBBBMO-UHFFFAOYSA-N |
| CAS DataBase Reference | 151-18-8(CAS DataBase Reference) |
| EPA Substance Registry System | Propanenitrile, 3-amino- (151-18-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H227-H301-H314-H318-H361 | |||||||||
| Precautionary statements | P210-P260-P264-P270-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P370+P378-P403+P235-P405-P501-P210e-P301+P310a-P303+P361+P353-P305+P351+P338-P501a | |||||||||
| Hazard Codes | Xn,C | |||||||||
| Risk Statements | 20/21/22-34-22-63 | |||||||||
| Safety Statements | 36/37-45-36/37/39-26 | |||||||||
| RIDADR | 3276 | |||||||||
| RTECS | UG0350000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| NFPA 704 |
|
3-Aminopropionitrile price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | CDS007521 | 3-amino-propionitrile AldrichCPR | 151-18-8 | 1G | ₹18023.63 | 2022-06-14 | Buy |
| ALFA India | ALF-A13043-14 | 3-Aminopropionitrile, 98%, stab. with potassium carbonate | 151-18-8 | 25g | ₹20500 | 2022-05-26 | Buy |
| ALFA India | ALF-A13043-06 | 3-Aminopropionitrile, 98%, stab. with potassium carbonate | 151-18-8 | 5g | ₹7289 | 2022-05-26 | Buy |
| ALFA India | ALF-A13043-03 | 3-Aminopropionitrile, 98%, stab. with potassium carbonate | 151-18-8 | 1g | ₹2276 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A0408 | 3-Aminopropionitrile (stabilized with K2CO3) min. 98.0 % | 151-18-8 | 25ML | ₹5900 | 2022-05-26 | Buy |
3-Aminopropionitrile Chemical Properties,Uses,Production
Chemical Properties
clear colourless to yellow liquid. 3-Aminopropionitrile, [151-18-8], 3-aminopropanenitrile, b-aminopropionitrile, H2N – CH2 – CH2CN, Mr 70.09, bp 185℃ (101.3 kPa), n20D 1.4396, is a colorless liquid which tends to slowly polymerize if stored in the presence of air. 3-Aminopropionitrile is prepared by the reaction of acrylonitrile with ammonia and is mainly used as an intermediate in the manufacture of b-alanine and pantothenic acid [48].
Uses
3-Aminopropionitrile is used for organic synthesis and as pharmaceutical intermediates. As an intermediate used in the manufacture of beta-alanine and pantothenic acid.
Definition
ChEBI: An aminopropionitrile carrying an amino group at the beta-position.
Safety Profile
Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. Nitriles usually have cyanide-like effects. See also CYANIDE. Easily oxidized and unstable. A storage hazard; it polymerizes to an explosive yellow solid. When heated to decomposition it emits toxic fumes of CNand NO,. For fire and explosion hazards see CYANIDE.
Metabolism
3-Aminopropionitrile is the compound present in some Lathyms species (Leguminosae), especially sweet-pea seeds (L. odoratus), causing osteolathyrism in man and animals. Although 3-aminopropionitrile is generally present in the fresh plant as the gama-glutamyl derivative, only the free amine is an effective lathyrogen.
Osteolathyrogens cause skeletal deformations due to interference with the cross-linking between polypeptide chains in the connective tissue components, elastin and collagen. This interference is partly due to inhibition of the synthesis of desmosine and isodesmosine, amino acids which effect the cross-linking in elastin. Cross-linking interference of collagen can be prevented in chicks by feed- ing excess calcium.
It is possible that 3-aminopropionitrile is adegradation product of 3-cyano-alanine, although in many plants the latter compound is converted to asparagine and it has not been detected in Lathyms species.
3-Aminopropionitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
| Manik Laboratories | +91-8121482049 +91-8121482049 | New Delhi, India | 49 | 58 | Inquiry |
| HEMANT BIOSCIENCE | 9848655224 | Telangana, India | 40 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3878 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| BTC pharm India | 58 |
| Manik Laboratories | 58 |
| HEMANT BIOSCIENCE | 58 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Clearsynth Labs | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| Hebei Mojin Biotechnology Co., Ltd | 58 |
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