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GALANIN, PORCINE

GALANIN, PORCINE Structure
CAS No.
88813-36-9
Chemical Name:
GALANIN, PORCINE
Synonyms
galanin;Ccris 6750;Pig galanin;GALANIN (PIG);Porcine galanin;GALANIN, PORCINE;Porcine galanin(1-29);Galanin(1-29) porcine;Mouse Anti-GAL antibody;Rabbit Anti-GAL antibody
CBNumber:
CB3156779
Molecular Formula:
C146H213N43O40
Molecular Weight:
3210.52
MOL File:
88813-36-9.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:05

GALANIN, PORCINE Properties

Density 1.50±0.1 g/cm3(Predicted)
RTECS LW5952050
storage temp. −20°C
form powder
color White to off-white
Water Solubility Soluble to 0.50 mg/ml in water
Sequence H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2

SAFETY

Risk and Safety Statements

WGK Germany  3

GALANIN, PORCINE Chemical Properties,Uses,Production

Biological Functions

Galanin is colocalized with acetylcholine, 5-HT , and NE in neurons or in brain regions implicated in cognitive and affective behavior, suggesting a possible role in the regulation of 5-HT and NA neurotransmission in depressive states and during the course of antidepressant therapy. Three galanin receptor subtypes have been cloned and studied, but little is known about their specific contributions to behavioral processes. In the CNS, galanin inhibits acetylcholine release, suggesting a possible role for galanin in cholinergic dysfunction; inhibits neurotransmitter release and neuronal firing rate; and inhibits signal transduction by inhibition of phosphatidyl inositol hydrolysis, leading to symptoms of depression. Thus, blocking the inhibitory effects of galanin on monoamine neurotransmitters with galanin receptor antagonists would be predicted to mimic or augment the action of the other monoamine classes of antidepressants."

Clinical Use

Since its discovery in 1983, the neuropeptide galanin has been found to be involved in a wide range of functions, including pain sensation, sexual activity, feeding, and learning and memory. Galanin is widely distributed in the central and peripheral nervous systems and in the endocrine system, and it acts as a inhibitory neuromodulator of NE and 5-HT in the brain. The 29- to 30-amino-acid sequence of galanin is conserved (almost 90% among species), indicating the importance of the molecule among species.

GALANIN, PORCINE Preparation Products And Raw materials

Raw materials

Preparation Products

GALANIN, PORCINE Suppliers

Global( 134)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Chengdu Youngshe Chemical Co., Ltd. +8618108235634 China 2345 58 Inquiry
Nanjing TGpeptide +86-13347807150 +86-13347807150 China 3279 58 Inquiry
GALANIN PORCINEGALANIN POR H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-HIS-ALA-ILE-ASP-ASN-HIS-ARG-SER-PHE-HIS-ASP-LYS-TYR-GLY-LEU-ALA-NH2 GALANIN (PIG) GALANIN, PORCINE GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-HIS-ALA-ILE-ASP-ASN-HIS-ARG-SER-PHE-HIS-ASP-LYS-TYR-GLY-LEU-ALA-NH2 GWTLNSAGYLLGPHAIDNHRSFHDKYGLA-NH2 Ccris 6750 Galanin(1-29) porcine L-Alaninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-histidyl-L-alanyl-L-isoleucyl-L-alpha-aspartyl-L-asparaginyl-L-histidyl-L-arginyl-L-seryl-L-phenylalanyl-L-histidyl-L-alpha-aspartyl-L-lysyl-L-tyrosylglycyl-L-leucyl- Porcine galanin Porcine galanin(1-29) Pig galanin Gly-L-Trp-L-Thr-L-Leu-L-Asn-L-Ser-L-Ala-Gly-L-Tyr-L-Leu-L-Leu-Gly-L-Pro-L-His-L-Ala-L-Ile-L-Asp-L-Asn-L-His-L-Arg-L-Ser-L-Phe-L-His-L-Asp-L-Lys-L-Tyr-Gly-L-Leu-L-Ala-NH2 Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-LLe-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2 galanin GALANIN, PORCINE USP/EP/BP Galanin, porcine, ≥97% (HPLC) Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-histidyl-L-alanyl-L-isoleucyl-L-a-aspartyl-L-asparaginyl-L-histidyl-L-arginyl-L-seryl-L-phenylalanyl-L-histidyl-L-a-aspartyl-L-lysyl- Mouse Anti-GAL antibody Rabbit Anti-GAL antibody 88813-36-9 C146H213N43O40 多肽抗原 小鼠抗大、小鼠、鸡、猪、牛多克隆抗体 Peptides Gastrointestinal Products Galanins BioChemical Biochemicals and Reagents Amino Acids and Peptides Peptide Galanins Neuropeptides Peptides for Cell Biology