GALANIN, PORCINE
![GALANIN, PORCINE Structure](CAS/GIF/88813-36-9.gif)
- CAS No.
- 88813-36-9
- Chemical Name:
- GALANIN, PORCINE
- Synonyms
- galanin;Ccris 6750;Pig galanin;GALANIN (PIG);Porcine galanin;GALANIN, PORCINE;Porcine galanin(1-29);Galanin(1-29) porcine;Mouse Anti-GAL antibody;Rabbit Anti-GAL antibody
- CBNumber:
- CB3156779
- Molecular Formula:
- C146H213N43O40
- Molecular Weight:
- 3210.52
- MOL File:
- 88813-36-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:05
Density | 1.50±0.1 g/cm3(Predicted) |
---|---|
RTECS | LW5952050 |
storage temp. | −20°C |
form | powder |
color | White to off-white |
Water Solubility | Soluble to 0.50 mg/ml in water |
Sequence | H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2 |
GALANIN, PORCINE Chemical Properties,Uses,Production
Biological Functions
Galanin is colocalized with acetylcholine, 5-HT , and NE in neurons or in brain regions implicated in cognitive and affective behavior, suggesting a possible role in the regulation of 5-HT and NA neurotransmission in depressive states and during the course of antidepressant therapy. Three galanin receptor subtypes have been cloned and studied, but little is known about their specific contributions to behavioral processes. In the CNS, galanin inhibits acetylcholine release, suggesting a possible role for galanin in cholinergic dysfunction; inhibits neurotransmitter release and neuronal firing rate; and inhibits signal transduction by inhibition of phosphatidyl inositol hydrolysis, leading to symptoms of depression. Thus, blocking the inhibitory effects of galanin on monoamine neurotransmitters with galanin receptor antagonists would be predicted to mimic or augment the action of the other monoamine classes of antidepressants."
Clinical Use
Since its discovery in 1983, the neuropeptide galanin has been found to be involved in a wide range of functions, including pain sensation, sexual activity, feeding, and learning and memory. Galanin is widely distributed in the central and peripheral nervous systems and in the endocrine system, and it acts as a inhibitory neuromodulator of NE and 5-HT in the brain. The 29- to 30-amino-acid sequence of galanin is conserved (almost 90% among species), indicating the importance of the molecule among species.
GALANIN, PORCINE Preparation Products And Raw materials
Raw materials
Preparation Products
GALANIN, PORCINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16208 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10318 | 58 | Inquiry |
Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 999 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25196 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | China | 2345 | 58 | Inquiry |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 | China | 3279 | 58 | Inquiry |
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