ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >Histamine Receptor Inhibitors >BUCLIZINE, DIHYDROCHLORIDE
BUCLIZINE, DIHYDROCHLORIDE
- CAS No.
- 129-74-8
- Chemical Name:
- BUCLIZINE, DIHYDROCHLORIDE
- Synonyms
- POSDEL;BUCLINA;softran;aphilanr;buclodin;UCB-4445;VIBAZINE;LONGIFENE;BUCLIZINE 2HCL;1-(4-(tert-Butyl)
- CBNumber:
- CB3156784
- Molecular Formula:
- C28H35Cl3N2
- Molecular Weight:
- 505.95
- MOL File:
- 129-74-8.mol
- Modify Date:
- 2023/5/18 11:31:10
Melting point | 230-240°C |
---|---|
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
form | powder |
color | white to beige |
Stability | Hygroscopic |
CAS DataBase Reference | 129-74-8 |
EPA Substance Registry System | Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride (129-74-8) |
BUCLIZINE, DIHYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
BUCLIZINE, DIHYDROCHLORIDE is Off-White Powder
Uses
BUCLIZINE, DIHYDROCHLORIDE used as an antiemetic
General Description
Buclizine hydrochloride, l-(p-tertbutylbenzyl)-4-(p-chloro-α-phenylbenzyl)piperazinedihydrochloride (Bucladin-S), is a white to slightly yellowcrystalline powder that is insoluble in water. The highlylipid-soluble buclizine has CNS depressant, antiemetic, andantihistaminic properties. This drug has been discontinued inthe United States.
Safety Profile
Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NOx, and HCl.
BUCLIZINE, DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 129)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
DK Pharmachem Pvt Ltd | +91-2242153111 +91-2242153111 | Maharashtra, India | 37 | 58 | Inquiry |
Fleming Laboratories Ltd | +91-9666407333 +91-9666022445 | Hyderabad, India | 22 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
SRIKEM LABORATORIES PVT LTD | +91-2224055088 +91-2224055088 | Maharashtra, India | 19 | 58 | Inquiry |
R L Fine Chem Pvt. Ltd | +91-8042488999 +91-8042488999 | Karnataka, India | 74 | 58 | Inquiry |
dkpharmachem | 91 -251 -2690366 | New Delhi, India | 60 | 46 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Jigs Chemical ltd | 58 |
DK Pharmachem Pvt Ltd | 58 |
Fleming Laboratories Ltd | 58 |
Ralington Pharma | 58 |
SRIKEM LABORATORIES PVT LTD | 58 |
R L Fine Chem Pvt. Ltd | 58 |
dkpharmachem | 46 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
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BUCLIZINE, DIHYDROCHLORIDE
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teratogen,Inhibitor,MCF-7,anti-tumor activity,antiallergic,antihistamine,inhibit,Histamine Receptor,Buclizine,Buclizine dihydrochloride
1-(4-(tert-butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine hydrochloride
129-74-8
C28H35Cl3N2
C28H33ClN22HCl
C28H37Cl3N2
C28H33ClN22ClH
Intermediates & Fine Chemicals
Pharmaceuticals
Inhibitors