Cyclizine

CAS No.: 82-92-8

Chemical Name:: Cyclizine

Synonyms: Valoid;Emoquil;bw47-83;Marzine;Bw 47-83;Marazine;Marezine;Wellcome;Ciclizina;Nautazine

CBNumber:: CB5336795

Molecular Formula:: C18H22N2

Molecular Weight:: 266.38

MOL File:: 82-92-8.mol

Modify Date:: 2024/7/2 8:55:11

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Cyclizine Properties

Melting point	105.5-107.5°
Boiling point	399.58°C (rough estimate)
Density	0.9934 (rough estimate)
refractive index	1.5840 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Slightly soluble in water and in ethanol (96 per cent).
form	Solid
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H319-H301-H335-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P310-P321-P330-P405-P501

Cyclizine Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

H1 antihistamine

Definition

ChEBI: An N-alkylpiperazine in which one nitrogen of the piperazine ring is substituted by a methyl group, while the other is substituted by a diphenylmethyl group.

Preparation

Cyclizine is prepared through the alkylation of N-methylpiperazine with benzhydryl chloride.

General Description

Cyclizine hydrochloride,1-(diphenylmethyl)-4-methylpiperazine monohydrochloride(Marezine), occurs as a light-sensitive, white crystallinepowder with a bitter taste. It is slightly soluble in water(1:115), in alcohol (1:115), and in chloroform (1:75). It isused primarily in the prophylaxis and treatment of motionsickness. The lactate salt (Cyclizine Lactate Injection,United States Pharmacopoeia [USP]) is used for intramuscular(IM) injection because of the limited water solubilityof the hydrochloride. The injection should be stored in acold place, because if it is stored at room temperature forseveral months, a slight yellow tint may develop. This doesnot indicate a loss in biologic potency.

Cyclizine Preparation Products And Raw materials

Raw materials

Chlorodiphenylmethane 1-Methylpiperazine

Preparation Products

Cyclizine Suppliers

Global( 68)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SRIKEM LABORATORIES PVT LTD	+91-2224055088 +91-2224055088	Maharashtra, India	19	58	Inquiry
MICRO LABS LIMITED	+91-80-2237 0451-57	New Delhi, India	15	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Srikem Laboratories Pvt.Ltd	08048372772Ext 723	Mumbai, India	10	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	China	34571	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	China	9030	58	Inquiry

Supplier	Advantage
SRIKEM LABORATORIES PVT LTD	58
MICRO LABS LIMITED	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Srikem Laboratories Pvt.Ltd	58
Pharma Affiliates	58
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58

82-92-8(Cyclizine)Related Search:

Cyclizine BUCLIZINE, DIHYDROCHLORIDE Cetirizine BUCLIZINE CHLORCYCLIZINE

CHLORCYCLIZINE HYDROCHLORIDE Flunarizine dihydrochloride Stugeron Hydroxyzine Meclozine

Clocinizine Meclizine dihydrochloride Hydroxyzine dihydrochloride Cyclizine Hydrochloride 1-BENZHYDRYLPIPERAZINE

2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride 2-(4-BENZHYDRYLPIPERAZINO)-6-PHENYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE HYDROXYZINE PAMOATE

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(n-benzhydryl)(n’-methyl)diethylenediamine (N-Benzhydryl)(N'-methyl)diethylenediamine 1-(diphenylmethyl)-4-methyl-piperazin 1-Benzhydryl-4-methylpiperazine 1-Diphenylmethyl-4-methylpiperazine Bw 47-83 bw47-83 Ciclizina Compound 47-83 compound47-83 Emoquil Marazine Marezine Marzine Nautazine n-benzhydryl-n’-methylpiperazine N-Benzhydryl-N-methyl piperazine N-Benzhydryl-N'-methylpiperazine 1-DIPHENYLMETHYL-4-METHYL-PIPERAZINE HYDROCHLORIDE n-benzhydryl-n-methylpiperazine Ne-devomit Neo-devomit n-methyl-n’-benzhydrylpiperazine n-methyl-n’-benzyhydrylpiperazine N-Methyl-N'-benzhydrylpiperazine N-Methyl-N'-benzyhydrylpiperazine Piperazine, 1-(diphenylmethyl)-4-methyl- Valoid Wellcome Wellcome preparation 47-83 Wellcome prepn. 47-83 wellcomepreparation47-83 N-BENZHYDRYL-N'-METHYLPIPERAZINE HYDROCHLORIDE CYCLIZINE HCL Cyclizine (base and/or unspecified salts) CYCLYZINE Cyclizine Base Cyclizine USP/EP/BP cyclizineis1-benzhydryl-4-methylpiperazine.itcontainsnotlessthan98.5%andnotmorethan101.0%ofc18h22N2,calculatedwithreferencetothedriedsubstance Cyclizine Secreizine in methanol 82-92-8 305-25-3 Miscellaneous