Meclizine dihydrochloride
- CAS No.
- 1104-22-9
- Chemical Name:
- Meclizine dihydrochloride
- Synonyms
- diadril;bonamine;NSC 28728;Navidoxine;Meclozine Hcl;)-4-(3-methyL;Meclizine 2HCl;Meclizine diHCl;Meclozine ,Bonamine;ancolandihydrochloride
- CBNumber:
- CB9362486
- Molecular Formula:
- C25H29Cl3N2
- Molecular Weight:
- 463.87
- MOL File:
- 1104-22-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 210.0 to 214.0 °C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| CAS DataBase Reference | 1104-22-9(CAS DataBase Reference) |
| EPA Substance Registry System | Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride (1104-22-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H361 | |||||||||
| Precautionary statements | P201-P301+P312+P330-P308+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-63 | |||||||||
| Safety Statements | 22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TL2005000 | |||||||||
| HS Code | 2933.59.8000 | |||||||||
| Toxicity | LD50 oral in mouse: 1600mg/kg | |||||||||
| NFPA 704 |
|
Meclizine dihydrochloride price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0950 | Meclizine dihydrochloride ≥97% (HPLC) | 1104-22-9 | 50MG | ₹11710.5 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M2755 | Meclizine Dihydrochloride | 1104-22-9 | 5G | ₹7700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M2755 | Meclizine Dihydrochloride | 1104-22-9 | 25G | ₹9800 | 2022-05-26 | Buy |
Meclizine dihydrochloride Chemical Properties,Uses,Production
Description
Meclizine is a histamine H1 receptor antagonist (Ki = 250 nM). Pretreatment with meclizine (2.5-30 mg/kg, i.p.) reduces ovalbumin-induced mast cell degranulation, edema, and leukocyte influx in rat lung. Formulations containing meclizine have been used in the treatment of motion sickness and vertigo.
Chemical Properties
White or yellowish-white, slightly hygroscopic, crystalline powder.
Uses
Meclizine Dihydrochloride is a histamine H1 receptor antagonist with antiemetic properties. Meclizine Dihydrochloride is a research product for neuroscience. This compound may exhibit neuroprotective properties.
Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cland NOx.
Solubility in organics
Meclizine dihydrochloride is readily soluble in chloroform and pyridine, slightly soluble in dilute acids and ethanol, and insoluble in water or ether.
Meclizine dihydrochloride Preparation Products And Raw materials
Global( 285)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Viyash Life Sciences Pvt Ltd | +91-4023635052 +91-4023635052 | Telangana, India | 213 | 58 | Inquiry |
| Calyx Chemicals and Pharmaceuticals Ltd | +919819317220 | Mumbai, India | 15 | 58 | Inquiry |
| J.B. Chemicals Pharmaceuticals Ltd. | +91-022-24822222 +91-02224822222 | Mumbai, India | 10 | 58 | Inquiry |
| Fleming Laboratories Ltd | +91-9666407333 +91-9666022445 | Hyderabad, India | 22 | 58 | Inquiry |
| DK Pharmachem Pvt Ltd | +91-2242153111 +91-2242153111 | Maharashtra, India | 37 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Cohance Lifesciences (Previously RA Chem Pharma Ltd) | +91-4044758595 +91-4044758595 | Telangana, India | 47 | 58 | Inquiry |
| Sri Krishna Pharmaceuticals Ltd | +91-4027177825 +91-8886992503 | Telangana, India | 13 | 58 | Inquiry |
| SRIKEM LABORATORIES PVT LTD | +91-2224055088 +91-2224055088 | Maharashtra, India | 19 | 58 | Inquiry |
1104-22-9(Meclizine dihydrochloride)Related Search:
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride
Meclozine Hcl
1-((4-Chlorophenyl)(phenyl)Methyl)-4-(3-Methylbenzyl)piperazine dihydrochloride
Meclizine 2HCl
Piperazine,1-[(4-chlorophenyl)phenylMethyl]-4-[(3-Methylphenyl)Methyl]-, hydrochloride(1:2)
1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine,hydrochloride (1:2)
1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-piperazine dihydrochloride
1-p-chlorbenzhydryl-m-methylbenzylpiperazinedihydrochloride
ancolandihydrochloride
bonamine
diadril
MECLIZINE DIHYDROCHLORIDE
1-([4-CHLOROPHENYL]PHENYLMETHYL)-4-([3-METHYLPHENYL]-METHYL)PIPERAZINE DIHYDROCHLORIDE
1-((4-chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)-piperazindih
1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)-piperazindihydrochlorid
1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazindihyd
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride (9CI)
Postafene dihydrochloride
Piperazine, 1-(p-chloro-.alpha.-phenylbenzyl)-4-(m-methylbenzyl)-, dihydrochloride
meclozinedihydrochloride
parachloraminedihydrochloride
Meclozine dihydrochloride monohydrate
Meclizine diHCl
1-(p-Chloro-a-phenylbenzyl)-4-(m-methylbenzyl)piperazine dihydrochloride
mecilizine hydrochloride
Navidoxine
NSC 28728
Piperazine, 1-(p-chloro-a-phenylbenzyl)-4-(m-methylbenzyl)-, dihydrochloride (6CI, 8CI)
1-((4-Chlorophenyl)(phenyl)methyl)-4-(3-methylbenzyl)p
Meclozine ,Bonamine
MeclizineDihydrochloride>
Meclozine dihydrochloride CRS
)piperazine dihydrochL
)-4-(3-methyL
1-(4-Chlorobenzhydryl)-4-(3-methylbenzyl)piperazine Dihydrochloride
Meclizine dihydrochloride USP/EP/BP
1104-22-9
C25H27Cl2N22HCl
C25H27ClN22ClH
C25H29Cl3N2
C25H27ClN22HCl
PROVOCHOLINE