Chlorpromazine hydrochloride
- CAS No.
- 69-09-0
- Chemical Name:
- Chlorpromazine hydrochloride
- Synonyms
- CHLORPROMAZINE HCL;Chlorpromazine hydrochloride CRS;promapar;sonazine;HEBANIL;promacid;taroctyl;neurazine;norcozine;propaphen
- CBNumber:
- CB1492923
- Molecular Formula:
- C17H20Cl2N2S
- Molecular Weight:
- 355.33
- MOL File:
- 69-09-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/4 15:29:52
| Melting point | 192-196°C |
|---|---|
| Density | 1.2221 (estimate) |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | Very soluble in water, freely soluble in ethanol (96 per cent). It decomposes on exposure to air and light. |
| form | Powder/Solution |
| color | White to off-white or clear colorless |
| PH | pH (50g/L, 25℃) : 4.0～5.0 |
| Water Solubility | >=10 g/100 mL at 24 ºC |
| Merck | 14,2185 |
| BRN | 3779989 |
| BCS Class | 3 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. Air and light sesnsitive. |
| CAS DataBase Reference | 69-09-0(CAS DataBase Reference) |
| EPA Substance Registry System | Chlorpromazine hydrochloride (69-09-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H330 | |||||||||
| Precautionary statements | P260-P264-P270-P271-P284-P304+P340+P310 | |||||||||
| Hazard Codes | T+,T,F | |||||||||
| Risk Statements | 25-26-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 28-36/37-45-16 | |||||||||
| RIDADR | UN 2811 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SO1750000 | |||||||||
| F | 3-10-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29173980 | |||||||||
| Toxicity | LD50 orally in rats: 225 mg/kg (Goldenthal) | |||||||||
| NFPA 704 |
|
Chlorpromazine hydrochloride price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C8138 | Chlorpromazine hydrochloride ≥98% (TLC) | 69-09-0 | 5G | ₹11701.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C8138 | Chlorpromazine hydrochloride ≥98% (TLC) | 69-09-0 | 25G | ₹39078.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C-904 | Chlorpromazine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 69-09-0 | 1ML | ₹2407.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C8138 | Chlorpromazine hydrochloride ≥98% (TLC) | 69-09-0 | 100G | ₹108931.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C0982 | Chlorpromazine hydrochloride meets USP testing specifications | 69-09-0 | 5G | ₹11712.65 | 2022-06-14 | Buy |
Chlorpromazine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Chlorpromazine hydrochloride is used in the treatment of schizophrenia; anti-emetic; as an antipsychotic in pills, injections, and suppositories; to relieve nausea and vomiting associated with malignant diseases. In veterinary medicine, it is used as an anti-emetic, tranquilizer and sedative. It has slight antihistaminic and anti adrenaline actions. It is a peripheral vasodilator and adepressant that blocks dopamine receptors in the central nervous system.
Definition
ChEBI: The hydrochloride salt of chlorpromazine.
General Description
White or creamy-white odorless crystalline powder with very bitter taste. pH (5% aqueous solution) 4.0-5.5. pH (10% aqueous solution) 4-5.
Air & Water Reactions
Decomposes on exposure to air and light. becoming yellow, pink and, finally, violet. Water soluble.
Reactivity Profile
Chlorpromazine hydrochloride is incompatible in aqueous solution with sodium salts of barbiturates and other alkaline solutions. Solutions may be stabilized by addition of antioxidants and storing under nitrogen.
Fire Hazard
Flash point data for Chlorpromazine hydrochloride are not available; however, Chlorpromazine hydrochloride is probably combustible.
Safety Profile
Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. An experimentalteratogen. Experimental reproductive effects. An anti-emetic and antipsychotic drug. Human systemic effects: anorexia (human), excitement, gastrointestinal changes, irritability, pulse rate increase, respiratory stimulation, rigidity, somnolence, sweating. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and SOx.
Chlorpromazine hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SKVen Technologies Pvt.Ltd. | +91-7032295152 +91-7032295152 | Hyderabad, India | 81 | 58 | Inquiry |
| R L Fine Chem Pvt. Ltd | +91-8042488999 +91-8042488999 | Karnataka, India | 74 | 58 | Inquiry |
| Meck Pharmaceuticals and Chemicals Pvt. Ltd. | +91-9898053709 +91-9898540709 | Gujarat, India | 44 | 58 | Inquiry |
| Solara Active Pharma Sciences Ltd | +91-8046632100 +91-7075706520 | Bangalore, India | 65 | 58 | Inquiry |
| Besil Chem LLP | +91-7760252666 +91-9880731835 | Bangalore, India | 163 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Biophore India Pharmaceuticals Pvt Ltd | +91-9100031592 +91-9030907714 | Telangana, India | 134 | 58 | Inquiry |
| Enaltec Labs Pvt Ltd | +91-9167119247 +91-9167119247 | Maharashtra, India | 49 | 58 | Inquiry |
| Raks Pharma Pvt Ltd | 08066085813Ext 651 | Andhra Pradesh, India | 19 | 58 | Inquiry |
| Sachem | 91-9810014878 | Delhi, India | 75 | 58 | Inquiry |
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