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Dexpanthenol

Dexpanthenol Structure
CAS No.
81-13-0
Chemical Name:
Dexpanthenol
Synonyms
D-PANTHENOL;Provitamin B5;D-PANTOTHENYL ALCOHOL;D-PANTOTHENOL;(R)-2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYLBUTYRAMIDE;Bepanthen;Pantol;Pantenyl;PROVITAMIN B;PANTHENOL, D-
CBNumber:
CB3169304
Molecular Formula:
C9H19NO4
Molecular Weight:
205.25
MOL File:
81-13-0.mol
MSDS File:
SDS
Modify Date:
2024/9/3 11:51:57

Dexpanthenol Properties

Melting point 64~69℃
alpha 30.5 º (c=5, H2O on anh. sub)
Boiling point 118-120 °C (2.7 mmHg)
Density 1.20 g/mL at 20 °C (lit.)
vapor pressure 0Pa at 25℃
refractive index 1.495-1.502
Flash point 118-120°C/0.02m
storage temp. 2-8°C
solubility DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka 13.03±0.20(Predicted)
form Viscous Liquid or Semi Solid
color Clear colorless to slightly yellow
PH pH (100g/l,25℃) : 8.5~10.5
optical activity [α]20/D +30±1°, c = 5% in H2O
Water Solubility soluble
Sensitive Hygroscopic
Merck 14,2947
BRN 1724947
InChIKey SNPLKNRPJHDVJA-ZETCQYMHSA-N
LogP -1.06 at 22℃
CAS DataBase Reference 81-13-0(CAS DataBase Reference)
NIST Chemistry Reference Dexpanthenol(81-13-0)
EPA Substance Registry System (+)-Panthenol (81-13-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-48-41-37/38-20/21/22
Safety Statements  23-24/25-45-36/37/39-26-22
WGK Germany  1
RTECS  ES4316000
3-10
TSCA  Yes
HS Code  29241990
Toxicity LD50 oral in mouse: 15gm/kg
NFPA 704
1
0 1

Dexpanthenol price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 76200 D-Panthenol ≥98.0% (NT) 81-13-0 25ML ₹4773.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR1228 Dexpanthenol Pharmaceutical Secondary Standard; Certified Reference Material 81-13-0 500MG ₹8346.08 2022-06-14 Buy
Sigma-Aldrich(India) 76200 D-Panthenol ≥98.0% (NT) 81-13-0 100ML ₹13812.7 2022-06-14 Buy
TCI Chemicals (India) P0692 D-Panthenol 81-13-0 25G ₹2300 2022-05-26 Buy
TCI Chemicals (India) P0692 D-Panthenol 81-13-0 500G ₹10800 2022-05-26 Buy
Product number Packaging Price Buy
76200 25ML ₹4773.83 Buy
PHR1228 500MG ₹8346.08 Buy
76200 100ML ₹13812.7 Buy
P0692 25G ₹2300 Buy
P0692 500G ₹10800 Buy

Dexpanthenol Chemical Properties,Uses,Production

Chemical Properties

clear colorless to slightly yellow viscous liquid

Uses

Dexpanthenol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques as well as partial least-squares multivariate calibration.

General Description

Dexpanthenol is an alcohol analog of pantothenic acid and an important component of parenterals, local cosmetic preparations and multi-vitamins. It has as much biological activity as pantothenic acid and is found to be stable in aqueous solution.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Contact allergens

Pan(to)thenol is the alcohol corresponding to pantothenic acid, of the vitamin B5 group. It is used as a food additive, and in skin and hair products as a conditioning agent. Contact dermatitis and urticaria have been reported.

Safety Profile

Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.

Purification Methods

Purify D-panthenol by distillation in vacuo. It is a slightly hygroscopic viscous oil and is soluble in H2O and organic solvents. It is hydrolysed by alkali and strong acid. [Rabin J Am Pharm Assoc (Sci Ed) 37 502 1948, Bonati & Pitré Farmaco Ed Scient 14 43 1959, Beilstein 4 IV 1652.]

Dexpanthenol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 655)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Unicorn Petroleum Industries Private Limited +91-2225299990 +91-9930731710 Maharashtra, India 22 58 Inquiry
Dadia Chemical Industries +91-9920521550 +91-9892510297 Maharashtra, India 18 58 Inquiry
Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) +91-1142631798 +91-9899000024 New Delhi, India 55 58 Inquiry
Vijaya Pharma And Life Science +91-8939866271 +91-8939866271 Tamil Nadu, India 320 58 Inquiry
Malladi Specialties Ltd. +91 (40) 2720-4991 New Delhi, India 20 50 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry

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