Dexpanthenol
![Dexpanthenol Structure](CAS/GIF/81-13-0.gif)
- CAS No.
- 81-13-0
- Chemical Name:
- Dexpanthenol
- Synonyms
- D-PANTHENOL;Provitamin B5;D-PANTOTHENYL ALCOHOL;D-PANTOTHENOL;(R)-2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYLBUTYRAMIDE;Bepanthen;Pantol;Pantenyl;PROVITAMIN B;PANTHENOL, D-
- CBNumber:
- CB3169304
- Molecular Formula:
- C9H19NO4
- Molecular Weight:
- 205.25
- MOL File:
- 81-13-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/9/3 11:51:57
Melting point | 64~69℃ |
---|---|
alpha | 30.5 º (c=5, H2O on anh. sub) |
Boiling point | 118-120 °C (2.7 mmHg) |
Density | 1.20 g/mL at 20 °C (lit.) |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.495-1.502 |
Flash point | 118-120°C/0.02m |
storage temp. | 2-8°C |
solubility | DMSO (Sparingly), Methanol (Slightly), Water (Sparingly) |
pka | 13.03±0.20(Predicted) |
form | Viscous Liquid or Semi Solid |
color | Clear colorless to slightly yellow |
PH | pH (100g/l,25℃) : 8.5~10.5 |
optical activity | [α]20/D +30±1°, c = 5% in H2O |
Water Solubility | soluble |
Sensitive | Hygroscopic |
Merck | 14,2947 |
BRN | 1724947 |
InChIKey | SNPLKNRPJHDVJA-ZETCQYMHSA-N |
LogP | -1.06 at 22℃ |
CAS DataBase Reference | 81-13-0(CAS DataBase Reference) |
NIST Chemistry Reference | Dexpanthenol(81-13-0) |
EPA Substance Registry System | (+)-Panthenol (81-13-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H332-H335 | |||||||||
Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 36/37/38-48-41-37/38-20/21/22 | |||||||||
Safety Statements | 23-24/25-45-36/37/39-26-22 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | ES4316000 | |||||||||
F | 3-10 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29241990 | |||||||||
Toxicity | LD50 oral in mouse: 15gm/kg | |||||||||
NFPA 704 |
|
Dexpanthenol price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 76200 | D-Panthenol ≥98.0% (NT) | 81-13-0 | 25ML | ₹4773.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1228 | Dexpanthenol Pharmaceutical Secondary Standard; Certified Reference Material | 81-13-0 | 500MG | ₹8346.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 76200 | D-Panthenol ≥98.0% (NT) | 81-13-0 | 100ML | ₹13812.7 | 2022-06-14 | Buy |
TCI Chemicals (India) | P0692 | D-Panthenol | 81-13-0 | 25G | ₹2300 | 2022-05-26 | Buy |
TCI Chemicals (India) | P0692 | D-Panthenol | 81-13-0 | 500G | ₹10800 | 2022-05-26 | Buy |
Dexpanthenol Chemical Properties,Uses,Production
Chemical Properties
clear colorless to slightly yellow viscous liquid
Uses
Dexpanthenol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques as well as partial least-squares multivariate calibration.
General Description
Dexpanthenol is an alcohol analog of pantothenic acid and an important component of parenterals, local cosmetic preparations and multi-vitamins. It has as much biological activity as pantothenic acid and is found to be stable in aqueous solution.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Contact allergens
Pan(to)thenol is the alcohol corresponding to pantothenic acid, of the vitamin B5 group. It is used as a food additive, and in skin and hair products as a conditioning agent. Contact dermatitis and urticaria have been reported.
Safety Profile
Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.
Purification Methods
Purify D-panthenol by distillation in vacuo. It is a slightly hygroscopic viscous oil and is soluble in H2O and organic solvents. It is hydrolysed by alkali and strong acid. [Rabin J Am Pharm Assoc (Sci Ed) 37 502 1948, Bonati & Pitré Farmaco Ed Scient 14 43 1959, Beilstein 4 IV 1652.]
Dexpanthenol Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Unicorn Petroleum Industries Private Limited | +91-2225299990 +91-9930731710 | Maharashtra, India | 22 | 58 | Inquiry |
Dadia Chemical Industries | +91-9920521550 +91-9892510297 | Maharashtra, India | 18 | 58 | Inquiry |
Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) | +91-1142631798 +91-9899000024 | New Delhi, India | 55 | 58 | Inquiry |
Vijaya Pharma And Life Science | +91-8939866271 +91-8939866271 | Tamil Nadu, India | 320 | 58 | Inquiry |
Malladi Specialties Ltd. | +91 (40) 2720-4991 | New Delhi, India | 20 | 50 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
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