BIOTIN HYDRAZIDE
- CAS No.
- 66640-86-6
- Chemical Name:
- BIOTIN HYDRAZIDE
- Synonyms
- Biotin-Hz;Biotin-NHNH2;CAS_66640-86-6;5-((3aS,4S,6aR);BIOTIN-Hydrazid;BIOTIN-HYDRAZIDE;BIOTIN HYDRAZIDE;Biontin-Hydrazide;Biotin Impurity 32;Biotinyl hydrazine
- CBNumber:
- CB3175354
- Molecular Formula:
- C10H18N4O2S
- Molecular Weight:
- 258.34
- MOL File:
- 66640-86-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/20 16:43:00
| Melting point | 245-247 °C |
|---|---|
| Boiling point | 633.1±40.0 °C(Predicted) |
| Density | 1.243±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≤20 mg/mL |
| form | powder |
| pka | 13.25±0.35(Predicted) |
| color | White to Almost white |
| BRN | 28347 |
| InChIKey | KOZWHQPRAOJMBN-ZKWXMUAHSA-N |
| CAS DataBase Reference | 66640-86-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
BIOTIN HYDRAZIDE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B7639 | (+)-Biotin hydrazide ≥97% (TLC), powder | 66640-86-6 | 100MG | ₹7729.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B7639 | (+)-Biotin hydrazide ≥97% (TLC), powder | 66640-86-6 | 1G | ₹50022.33 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B2431 | Biotin Hydrazide | 66640-86-6 | 25MG | ₹2600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B2431 | Biotin Hydrazide | 66640-86-6 | 100MG | ₹6800 | 2022-05-26 | Buy |
BIOTIN HYDRAZIDE Chemical Properties,Uses,Production
Description
Biotin hydrazide is a biotinyl derivative used to label surface functional groups, antibodies, lectins, sugars, nucleic acids, or molecules with free carboxylic or keto groups. Biotin hydrazide is used as a probe for determining protein carbonylation, an irreversible posttranslational modification resulting from the actions of reactive oxygen species or lipid oxidation products. The reaction of this probe is direct and does not require catalysts or reducing agents.
Chemical Properties
3.6
Uses
Biotin Hydrazide is a carbohydrate reactive biotinylation reagent used predominately for labeling monoclonal antibodies, unpaired cytosine residues in nucleic acids and glycoproteins.
General Description
Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties. Biotin hydrazide can be used to prepare biotin-conjugated alginate. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.
Purification Methods
Wash the hydrazide with H2O, dry it, wash it with MeOH then Et2O, and dry. Recrystallise it from hot H2O (clusters of prisms) [Hofmann et al. J Biol Chem 144 513 1942]. [Beilstein 27 III/IV 7980.]
BIOTIN HYDRAZIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | China | 2931 | 58 | Inquiry |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | China | 2169 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |