Succinimidyl 6-(biotinamido)hexanoate

- CAS No.
- 72040-63-2
- Chemical Name:
- Succinimidyl 6-(biotinamido)hexanoate
- Synonyms
- Bachs;BIOTIN-X-NHS;BIOTIN-X, SE;NHS-X-Biotin;D-Biotiamide;NHS-LC-BIOTIN;BIOTIN-LC-OSU;Biotin-LC-NHS;Biotin-NHS LC;BIOTIN-AC5-OSU
- CBNumber:
- CB2343655
- Molecular Formula:
- C20H30N4O6S
- Molecular Weight:
- 454.54
- MOL File:
- 72040-63-2.mol
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 169-171 °C |
---|---|
Density | 1.35±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | H2O: ≤2 mg/mL with sonication |
form | powder |
pka | 13.90±0.40(Predicted) |
color | White to Off-White |
Water Solubility |
H2O: ≤2mg/mL (with sonication) DMF: 50mg/mL (Stable up to 2 months in dry DMF.) |
BRN | 3577403 |
Stability | Moisture Sensitive |
InChIKey | UVGHPGOONBRLCX-NJSLBKSFSA-N |
CAS DataBase Reference | 72040-63-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H332-H335 | |||||||||
Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-21 | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
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Succinimidyl 6-(biotinamido)hexanoate price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | B2643 | Biotinamidohexanoic acid N-hydroxysuccinimide ester ≥98% (TLC), powder | 72040-63-2 | 10MG | ₹4308.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B2643 | Biotinamidohexanoic acid N-hydroxysuccinimide ester ≥98% (TLC), powder | 72040-63-2 | 25MG | ₹9385.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B2643 | Biotinamidohexanoic acid N-hydroxysuccinimide ester ≥98% (TLC), powder | 72040-63-2 | 100MG | ₹29725.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B2643 | Biotinamidohexanoic acid N-hydroxysuccinimide ester ≥98% (TLC), powder | 72040-63-2 | 250MG | ₹63802.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 203189 | Biotin-X-NHS, Water-Soluble | 72040-63-2 | 50MG | ₹60330 | 2022-06-14 | Buy |
Succinimidyl 6-(biotinamido)hexanoate Chemical Properties,Uses,Production
Chemical Properties
Succinimidyl 6-(biotinamido)hexanoate is White Solid
Uses
Succinimidyl 6-(biotinamido)hexanoate is a biotinylation reagent incorporating an aminocaproyl “spacer”. This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture System. This system avoids the direct interaction of a captured antibody with solid surfaces, such as plastics, which may reduce antigenicity. It has also been used to enhance the detection of DNA on nitrocellulose. Has also been used as a cell surface labelling reagent
Purification Methods
Dissolve ~400mg of the ester in dry propan-2-ol (~25mL) with gentle heating. Reduce the volume to ~10mL by gentle boiling and allow the solution to cool. Decant the supernatant carefully from the white crystals, dry the crystals in a vacuum over P2O5 at 60o overnight. This material gives one spot on TLC. [Costello et al. Clin Chem 25 1572 1979, Kincaid et al. Methods Enzymol 159 619 1988.]
Succinimidyl 6-(biotinamido)hexanoate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29858 | 58 | Inquiry |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | China | 2930 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | China | 9304 | 58 | Inquiry |