N-(2-Acetamido)iminodiacetic acid
- CAS No.
- 26239-55-4
- Chemical Name:
- N-(2-Acetamido)iminodiacetic acid
- Synonyms
- ADA;ADA,97%;ADA,98+%;ADA buffe;ADA BUFFER;Adogen 342D;ADA FREE ACID;ADA buffe ADA;ADA SIGMAULTRA;Einecs 247-530-0
- CBNumber:
- CB3183520
- Molecular Formula:
- C6H10N2O5
- Molecular Weight:
- 190.15
- MOL File:
- 26239-55-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/29 17:07:33
| Melting point | 219 °C (dec.)(lit.) |
|---|---|
| Boiling point | 325.64°C (rough estimate) |
| Density | 1.4957 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5010 (estimate) |
| storage temp. | room temp |
| solubility | 1 M NaOH: 0.05 M at 20 °C, clear, colorless |
| form | Powder |
| color | White to almost white |
| PH | 1.5-3.0 (25℃, 0.01M in H2O) |
| pka | 6.6(at 25℃) |
| PH Range | 6.0 - 7.2 |
| Water Solubility | soluble |
| λmax |
λ: 260 nm Amax: 0.20 λ: 280 nm Amax: 0.05 |
| Merck | 14,147 |
| BRN | 1787181 |
| InChIKey | QZTKDVCDBIDYMD-UHFFFAOYSA-N |
| LogP | -3.12 at 20℃ |
| CAS DataBase Reference | 26239-55-4(CAS DataBase Reference) |
| EPA Substance Registry System | Glycine, N-(2-amino-2-oxoethyl)-N-(carboxymethyl)- (26239-55-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29241900 | |||||||||
| NFPA 704 |
|
N-(2-Acetamido)iminodiacetic acid price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A9883 | ADA ≥98% (titration) | 26239-55-4 | 25G | ₹3063.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9883 | ADA ≥98% (titration) | 26239-55-4 | 100G | ₹7220.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9883 | ADA ≥98% (titration) | 26239-55-4 | 250G | ₹11355.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9883 | ADA ≥98% (titration) | 26239-55-4 | 1KG | ₹44101.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 00307 | ADA BioUltra, ≥99.0% (T) | 26239-55-4 | 5G | ₹2186.65 | 2022-06-14 | Buy |
N-(2-Acetamido)iminodiacetic acid Chemical Properties,Uses,Production
Description
N-(2-Acetamido)iminodiacetic acid is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.
Chemical Properties
N-(2-Acetamido)iminodiacetic acid is white to almost white powder
Uses
N-(2-Acetamido)iminodiacetic acid (ADA) could prevents oxidation and irreversible denaturation of proteins while conducting gel electrophoresis. Furthermore studies suggest that ADA interferes with BCA and Lowry protein assays. Also ADA often chelates metal ions such as Mn(II), Cu(II), Ni(II), Zn(II), and Co(II) in a 2:1 at or below physiological pH values. Moreover, ADA is soluble in sodium hydroxide and absorbs UV radiation in the range below 260nm.
Uses
N-(2-Acetamido)iminodiacetic acid is buffer for biological systems and chelator for metals.
Application
ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients.
Purification Methods
Dissolve ADA in water, add one equivalent of NaOH solution (to final pH of 8-9), then acidify with HCl to precipitate the free acid. This is filtered off, washed with water and dried in vacuo. [Beilstein 4 IV 2441.]
N-(2-Acetamido)iminodiacetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Real Chemsys Products Pvt Limited | +91-1204216880 +91-1204212000 | New Delhi, India | 29 | 58 | Inquiry |
| Spectrochem Private Limited | 08048372608Ext 246 | Maharashtra, India | 1056 | 58 | Inquiry |
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